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Please use this identifier to cite or link to this item:
http://arca.icict.fiocruz.br/handle/icict/559
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| Title: | Human immunodeficiency virus/acquired immunodeficiency syndrome and tropical diseases: a brazilian perspective |
| Authors: | Morgado, Mariza Gonçalves
Barcellos, Christovam de Castro
Pina, Maria de Fátima Rodrigues Pereira de
Bastos, Francisco Inácio Pinkusfeld Monteiro |
| Affilliation: | Laboratório de Aids e Imunologia Molecular, Departamento de Imunologia, Instituto Oswaldo Cruz
Departamento de Informações em Saúde, Centro de Informação Científica e Tecnológica-Fiocruz, UNAIDS Collaborating Centre
Departamento de Informações em Saúde, Centro de Informação Científica e Tecnológica-Fiocruz, UNAIDS Collaborating Centre
Departamento de Informações em Saúde, Centro de Informação Científica e Tecnológica-Fiocruz, UNAIDS Collaborating Centre |
| Keywords: | human immunodeficiency virus/acquired
immunodeficiency syndrome
HIV/Aids
co-infections
Brazil |
| Issue Date: | 2000 |
| Publisher: | Fundação Oswaldo Cruz |
| Source: | MORGADO, Mariza G. et al. Human immunodeficiency virus/acquired immunodeficiency syndrome and tropical diseases: a brazilian perspective. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95 (suppl. I), p. 145-151, 2000. |
| Abstract: | The paper summarizes recent findings on the epidemiology and pathogenesis of human immunodeficiency
virus/acquired immunodeficiency syndrome (HIV/Aids), highlighting the role of co-infections with
major tropical diseases. Such co-infections have been studied in the Brazilian context since the beginning
of the Aids epidemic and are expected to be more frequent and relevant as the Aids epidemic in Brazil
proceeds towards smaller municipalities and the countryside, where tropical diseases are endemic. Unlike
opportunistic diseases that affect basically the immunocompromised host, most tropical diseases, as well
as tuberculosis, are pathogenic on their own, and can affect subjects with mild or no immunossuppression.
In the era of highly active anti-retroviral therapies (HAART), opportunistic diseases seem to be on decrease
in Brazil, where such medicines are fully available. Benefiting from HAART in terms of restoration
of the immune function, putative milder clinical courses are expected in the future for most co-infections,
including tropical diseases. On the other hand, from an ecological perspective, the progressive geographic
diffusion of Aids makes tropical diseases and tuberculosis a renewed challenge for Brazilian researchers
and practitioners dealing with HIV/Aids in the coming years. |
| Description: | Mariza G Morgado, Christovam Barcellos*, Maria de Fátima Pina*, Francisco Inácio Bastos* Laboratório de Aids e Imunologia Molecular, Departamento de Imunologia, Instituto Oswaldo Cruz
*Departamento de Informações em Saúde, Centro de Informação Científica e Tecnológica-Fiocruz, UNAIDS Collaborating Centre, Av. Brasil 4365, 21045-900 Rio de Janeiro, RJ, Brasil |
| ISSN: | 0074-0276 |
| Appears in Collections: | ICICT - Artigos de Periódicos
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