Author | Teixeira, Maria da Gloria Lima Cruz | |
Author | Paixão, Enny Santos da | |
Author | Costa, Maria da Conceição Nascimento | |
Author | Cunha, Rivaldo Venâncio da | |
Author | Cavalcanti, Luciano Pamplona de Goes | |
Author | Dias, Juarez Perez | |
Author | Figueiredo, Camila Alexandrina Viana | |
Author | Figueiredo, Maria Aparecida A | |
Author | Blanton, Ronald Edward | |
Author | Morato, Vanessa G. | |
Author | Barreto, Maurício Lima | |
Author | Rodrigues, Laura C | |
Access date | 2015-07-09T17:40:35Z | |
Available date | 2015-07-09T17:40:35Z | |
Document date | 2015 | |
Citation | TEIXEIRA, M. G. L. C. et al. Arterial hypertension and skin allergy are risk factors for progression from dengue to dengue hemorrhagic Fever: a case control study. PLoS Neglected Tropical Diseases, v. 9, n. 5, p. e0003812, 2015 | pt_BR |
ISSN | 1935-2727 | |
URI | https://www.arca.fiocruz.br/handle/icict/11199 | |
Language | por | pt_BR |
Publisher | Public Library of Science | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Dengue | pt_BR |
Subject in Portuguese | Febre Hemorragica da Dengue | pt_BR |
Subject in Portuguese | Dengue Hemorragica | pt_BR |
Subject in Portuguese | Humanos | pt_BR |
Subject in Portuguese | Mortalidade | pt_BR |
Subject in Portuguese | Hipertensão Arterial | pt_BR |
Subject in Portuguese | Alergia | pt_BR |
Subject in Portuguese | Fatores de Risco | pt_BR |
Subject in Portuguese | Pele | pt_BR |
Title | Arterial hypertension and skin allergy are risk factors for progression from dengue to dengue hemorrhagic Fever: a case control study. | pt_BR |
Type | Article | pt_BR |
Abstract | BACKGROUND: Currently, knowledge does not allow early prediction of which cases of dengue fever (DF) will progress to dengue hemorrhagic fever (DHF), to allow early intervention to prevent progression or to limit severity. The objective of this study is to investigate the hypothesis that some specific comorbidities increase the likelihood of a DF case progressing to DHF. METHODS: A concurrent case-control study, conducted during dengue epidemics, from 2009 to 2012. Cases were patients with dengue fever that progressed to DHF, and controls were patients of dengue fever who did not progress to DHF. Logistic regression was used to estimate the association between DHF and comorbidities. RESULTS: There were 490 cases of DHF and 1,316 controls. Among adults, progression to DHF was associated with self-reported hypertension (OR = 1.6; 95% CI 1.1-2.1) and skin allergy (OR = 1.8; 95% CI 1.1-3.2) with DHF after adjusting for ethnicity and socio-economic variables. There was no statistically significant association between any chronic disease and progression to DHF in those younger than 15 years. CONCLUSIONS: Physicians attending patients with dengue fever should keep those with hypertension or skin allergies in health units to monitor progression for early intervention. This would reduce mortality by dengue. | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal de Mato Grosso do Sul. Faculdade de Medicina. Mato Grosso do Sul, Brasil | pt_BR |
Affilliation | Universidade Federal do Ceará. Instituto de Ciências da Saúde. Fortaleza, CE, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Ciencias da Vida. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Case Western Reserve University. Cleveland, Ohio, USA | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | London School of Hygiene and Tropical Medicine. London, United Kingdom | pt_BR |