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Autor | Jeremias, Wander de Jesus | |
Autor | Melo, Jose Renan da Cunha | |
Autor | Baba, Elio Hideo | |
Autor | Coelho, Paulo Marcos Zech | |
Autor | Kusel, John Robert | |
Fecha de acceso | 2016-02-12T12:45:10Z | |
Fecha de disponibilización | 2016-02-12T12:45:10Z | |
Fecha de publicación | 2015 | |
Referencia | JEREMIAS, Wander de Jesus et al. The skin migratory stage of the schistosomulum of Schistosoma mansoni has a surface showing greater permeability and activity in membrane internalisation than other forms of skin or mechanical schistosomula. Parasitology, Vol. 142, n. 9, p. 1143-1151, 2015 | pt_BR |
ISSN | 0031-1820 | |
URI | https://www.arca.fiocruz.br/handle/icict/12718 | |
Idioma | eng | pt_BR |
Editor | Cambridge University Press | pt_BR |
Derechos de autor | restricted access | pt_BR |
Título | The skin migratory stage of the schistosomulum of Schistosoma mansoni has a surface showing greater permeability and activity in membrane internalisation than other forms of skin or mechanical schistosomula | pt_BR |
Tipo del documento | Article | pt_BR |
DOI | 10.1017/S0031182015000335 | |
Resumen en Inglés | Skin schistosomula can be prepared by collecting them after isolated mouse skin have been penetrated by cercariae in vitro. The schistosomula can also migrate out of isolated mouse skin penetrated by cercariae in vitro and from mouse skin penetrated by cercariae in vivo. Schistosomula can also be produced from cercariae applied through a syringe or in a vortex. When certain surface properties of the different forms of schistosomula were compared, those migrating from mouse skin penetrated by cercariae in vivo or in vitro had greatly increased permeability to membrane impermeant molecules such as Lucifer yellow and high molecular weight dextrans. These migrating forms also possessed surfaces which showed greatly enhanced uptake into internal membrane vesicles of the dye FM 143, a marker for endocytosis. This greatly enhanced activity and permeability of the surfaces of tissue migrating schistosomula is likely to be of great importance in the adaptation to the new host. | pt_BR |
Afiliación | Fundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratorio de Esquistossomose. Belo Horizonte, MG, Brasil | pt_BR |
Afiliación | Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Cirurgia. Belo Horizonte, MG, Brazil | pt_BR |
Afiliación | Fundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratorio de Esquistossomose. Belo Horizonte, MG, Brasil | pt_BR |
Afiliación | Fundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratorio de Esquistossomose. Belo Horizonte, MG, Brasil | pt_BR |
Afiliación | Glasgow University. Centre for Open Studies. Glasgow, UK | pt_BR |
Palavras clave en Inglês | Schistosomula | pt_BR |
Palavras clave en Inglês | surface membrane | pt_BR |
Palavras clave en Inglês | permeability | pt_BR |
Palavras clave en Inglês | endocytosis | pt_BR |