Autor | Pereira, Joseane Simone de Oliveira | |
Autor | Silva, Lidiane Rodrigues da | |
Autor | Nunes, Amanda de Meireles | |
Autor | Oliveira, Silas de Souza | |
Autor | Costa, Eliane Veiga da | |
Autor | Silva, Edson Elias da | |
Data de acesso | 2016-06-02T13:32:43Z | pt_BR |
Data de acesso | 2016-06-03T12:34:15Z | |
Data de disponibilização | 2016-06-02T13:32:43Z | pt_BR |
Data de disponibilização | 2016-06-03T12:34:15Z | |
Data do publicação | 2016 | pt_BR |
Citação | PEREIRA, Joseane Simone de Oliveira; et al. Environmental Surveillance of Polioviruses in Rio de Janeiro, Brazil, in Support to the Activities of Global Polio Eradication Initiative. Food Environ Virol., v.8, n.1, p.27-33, Mar. 2016. | pt_BR |
ISSN | 1867-0334 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/14424 | |
Idioma | eng | pt_BR |
Editor | Springer Verlag | pt_BR |
Direito Autoral | open access | pt_BR |
Palavras-chave | Erradicação da pólio | pt_BR |
Palavras-chave | Vigilância ambiental | pt_BR |
Palavras-chave | Poliomielite | pt_BR |
Palavras-chave | Rio de Janeiro | pt_BR |
Título | Environmental Surveillance of Polioviruses in Rio de Janeiro, Brazil, in Support to the Activities of Global Polio Eradication Initiative | pt_BR |
Tipo do documento | Article | pt_BR |
DOI | 10.1007/s12560-015-9221-5 | pt_BR |
Resumo em Inglês | Wild polioviruses still remain endemic in three countries (Afghanistan, Pakistan, and Nigeria) and re-emergency of wild polio has been reported in previously polio-free countries. Environmental surveillance has been used as a supplementary tool in monitoring the circulation of wild poliovirus (PVs) and/or vaccine-derived PVs even in the absence of acute flaccid paralysis cases. This study aimed to monitor the presence of polioviruses in wastewater samples collected at one wastewater treatment plant located in the municipality of Rio de Janeiro, Brazil. From December 2011 to June 2012 and from September to December 2012, 31 samples were collected and processed. RD and L20B cell cultures were able to isolate PVs and non-polio enteroviruses in 27/31 samples. Polioviruses were isolated in eight samples (type 1 Sabin = 1, type 2 Sabin = 5, and type 3 Sabin = 2). Vaccine-derived polioviruses were not detected nor evidence of recombination with other PVs or non-polio enterovirus serotypes were observed among the isolates. The Sabin-related serotypes 2 and 3 presented nucleotide substitutions in positions associated with the neurovirulent phenotype at the 5'-UTR. Changes in important Amino acid residues at VP1 were also observed in the serotypes 2 and 3. Environmental surveillance has been used successfully in monitoring the circulation of PVs and non-polio enteroviruses and it is of crucial importance in the final stages of the WHO global polio eradication initiative. Our results show the continuous circulation of Sabin-like PVs and non-polio enteroviruses in the analyzed area during the study period. | pt_BR |
Afiliação | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Afiliação | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Afiliação | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Afiliação | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Afiliação | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Afiliação | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovírus. Rio de Janeiro, RJ, Brasil. | pt_BR |
Palavras-chave em inglês | Environmental surveillance | pt_BR |
Palavras-chave em inglês | Polio eradication | pt_BR |
Palavras-chave em inglês | Poliomyelitis | pt_BR |
Palavras-chave em inglês | Poliovirus | pt_BR |
Palavras-chave em inglês | Brazil | pt_BR |
e-ISSN | 1867-0342 | pt_BR |