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https://www.arca.fiocruz.br/handle/icict/16744
Tipo de documento
ArtigoDireito Autoral
Acesso restrito
Data de embargo
2025-01-01
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RECENT ADVANCES IN SCHISTOSOMA GENOMICS
Autor(es)
Afiliação
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo de Genomica e Biologia Computacional. Belo Horizonte, MG, Brasil /Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Belo Horizonte, MG, Brasil
Université de Perpignan Via Domitia. Laboratoire Ecologie et Evolution des Interactions .Perpignan Cedex, France
University of Texas Health Science Center. Departments of Biochemistry and Pathology. San Antonio, TX, USA
University of Queensland. Queensland Institute of Medical Research. School of Veterinary Sciences. Herston, Qld, Australia
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo de Genomica e Biologia Computacional. Belo Horizonte, MG, Brasil /Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Belo Horizonte, MG, Brasil
Université de Perpignan Via Domitia. Laboratoire Ecologie et Evolution des Interactions .Perpignan Cedex, France
University of Texas Health Science Center. Departments of Biochemistry and Pathology. San Antonio, TX, USA
University of Queensland. Queensland Institute of Medical Research. School of Veterinary Sciences. Herston, Qld, Australia
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo de Genomica e Biologia Computacional. Belo Horizonte, MG, Brasil /Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais. Belo Horizonte, MG, Brasil
Resumo em Inglês
Schistosome research has entered the genomic era with the publications reporting the Schistosoma mansoni and Schistosoma japonicum genomes. Schistosome genomics is motivated by the need for new control tools. However, much can also be learned about the biology of Schistosoma, which is a tractable experimental model. In this article, we review the recent achievements in the field of schistosome research and discuss future perspectives on genomics and how it can be integrated in a usable format, on the genetic mapping and how it has improved the genome assembly and provided new research approaches, on how epigenetics provides interesting insights into the biology of the species and on new functional genomics tools that will contribute to the understanding of the function of genes, many of which are parasite- or taxon specific.
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