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https://www.arca.fiocruz.br/handle/icict/18433
PREVALENCE, AWARENESS, TREATMENT, AND CONTROL OF HIGH LOW-DENSITY LIPOPROTEIN CHOLESTEROL IN BRAZIL: BASELINE OF THE BRAZILIAN LONGITUDINAL STUDY OF ADULT HEALTH (ELSA-BRASIL)
Author
Affilliation
University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil
University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil
Federal University S.Joao Del Rei. São João Del Rei, BH, Brazil / Federal University Minas Gerais. Minas Gerais, BH, Brazil
University of Sao Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil / University of Sao Paulo. Heart Institute. São Paulo, SP, Brazil
Federal University Espirito Santo. Vitoria, ES, Brazil
Federal University Bahia. Salvador, BA, Brazil
Oswaldo Cruz Foundation. Rio de Janeiro, RJ, Brazil
Federal University Bahia. Salvador, BA, Brazil
Federal University Espirito Santo. Vitoria, ES, Brazil
Oswaldo Cruz Foundation. Rio de Janeiro, RJ, Brazil
Federal University Rio Grande do Sul. Department of Preventive Medicine. Porto Alegre, RGS, Brasil
Federal University of Minas Gerais. Department of Internal Medicine. Minas Gerais, BH, Brazil
Federal University Rio Grande do Sul. Department of Preventive Medicine. Porto Alegre, RGS, Brasil
University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil
University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil
Federal University S.Joao Del Rei. São João Del Rei, BH, Brazil / Federal University Minas Gerais. Minas Gerais, BH, Brazil
University of Sao Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil / University of Sao Paulo. Heart Institute. São Paulo, SP, Brazil
Federal University Espirito Santo. Vitoria, ES, Brazil
Federal University Bahia. Salvador, BA, Brazil
Oswaldo Cruz Foundation. Rio de Janeiro, RJ, Brazil
Federal University Bahia. Salvador, BA, Brazil
Federal University Espirito Santo. Vitoria, ES, Brazil
Oswaldo Cruz Foundation. Rio de Janeiro, RJ, Brazil
Federal University Rio Grande do Sul. Department of Preventive Medicine. Porto Alegre, RGS, Brasil
Federal University of Minas Gerais. Department of Internal Medicine. Minas Gerais, BH, Brazil
Federal University Rio Grande do Sul. Department of Preventive Medicine. Porto Alegre, RGS, Brasil
University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil
Abstract
Dyslipidemia is a pivotal risk factor for coronary heart disease (CHD). The purpose of this study was to identify the profile of dyslipidemia in a Brazilian population, according to high low-density lipoprotein (LDL-C) levels. We used the classification of the 2004 update of National Cholesterol Education Program Adult Treatment Panel III (ATP-III). METHODS: Of the 15,105 men and women aged 35 to 74 years enrolled in the Brazilian
Longitudinal Study of Adult Health (ELSA-Brasil), we included 14,648 subjects (97%). They had
data to categorize them according to the NCEP-ATP-III criteria. We compared 4 categories: ‘‘0–1’’
risk factors, ‘‘2 or more risk factors’’, ‘‘CHD or CHD risk equivalent’’, and ‘‘CHD at very high
risk’’. The sociodemographic determinants used were sex, age, ethnicity, income, education, and health
insurance. Poisson regression was used to estimate the prevalence ratios for cholesterol (LDL-C),
frequency, awareness, treatment, and control of high LDL-C. RESULTS: The frequencies of high LDL-C, awareness, treatment, and control were 45.5%, 58.1%,
42.3%, and 58.3%, respectively. After adjustment for sociodemographic determinants, the prevalence
ratios for high LDL-C were significantly higher for men, blacks, older subjects, and subjects with lower
levels of education. Low frequency of awareness, treatment, and uncontrolled values of LDL-C was
observed among men, mixed race and blacks, poorer, less educated, and those who did not have private
health insurance.
CONCLUSIONS: The prevalence of high LDL-C was elevated in this Brazilian population, with low
rates of awareness, treatment and control, and remarkable socioeconomic disparity.
2016 National Lipid Association. All rights reserved.
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