Author | Lotufo, Paulo Andrade | |
Author | Santos, Raul D | |
Author | Figueiredo, Roberta M | |
Author | Pereira, Alexandre C | |
Author | Mill, Jose Geraldo | |
Author | Alvim, Sheila Maria | |
Author | Fonseca, M Jesus | |
Author | Almeida, Maria da Conceição Chagas de | |
Author | Molina, M Carmen | |
Author | Chor, Dora | |
Author | Schmidt, Maria Inês | |
Author | Ribeiro, Antonio L | |
Author | Duncan, Bruce B | |
Author | Bensenor, Isabela Judith Martins | |
Access date | 2017-04-12T18:58:05Z | |
Available date | 2017-04-12T18:58:05Z | |
Document date | 2016 | |
Citation | LOTUFO, P. A. et al. Prevalence, awareness, treatment, and control of high low-density lipoprotein cholesterol in Brazil: Baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Journal of Clinical Lipidology, v. 10, p. 568–576, 2016. | pt_BR |
ISSN | 1933-2874 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/18433 | |
Description | Almeida, Maria da Conceição Chagas de. Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
“Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. | pt_BR |
Sponsorship | Brazilian Ministry of Health (Science and Technology Department) and the Brazilian Ministry of Science and Technology (Financiadora de Estudos e Projetos and CNPq National Research Council. | pt_BR |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Dislipidemia | pt_BR |
Subject in Portuguese | Estatinas | pt_BR |
Subject in Portuguese | Doença coronária | pt_BR |
Subject in Portuguese | Epidemiologia | pt_BR |
Subject in Portuguese | Fatores de risco | pt_BR |
Title | Prevalence, awareness, treatment, and control of high low-density lipoprotein cholesterol in Brazil: Baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.jacl.2015.12.029 | |
Abstract | Dyslipidemia is a pivotal risk factor for coronary heart disease (CHD). The purpose of this study was to identify the profile of dyslipidemia in a Brazilian population, according to high low-density lipoprotein (LDL-C) levels. We used the classification of the 2004 update of National Cholesterol Education Program Adult Treatment Panel III (ATP-III). METHODS: Of the 15,105 men and women aged 35 to 74 years enrolled in the Brazilian
Longitudinal Study of Adult Health (ELSA-Brasil), we included 14,648 subjects (97%). They had
data to categorize them according to the NCEP-ATP-III criteria. We compared 4 categories: ‘‘0–1’’
risk factors, ‘‘2 or more risk factors’’, ‘‘CHD or CHD risk equivalent’’, and ‘‘CHD at very high
risk’’. The sociodemographic determinants used were sex, age, ethnicity, income, education, and health
insurance. Poisson regression was used to estimate the prevalence ratios for cholesterol (LDL-C),
frequency, awareness, treatment, and control of high LDL-C. RESULTS: The frequencies of high LDL-C, awareness, treatment, and control were 45.5%, 58.1%,
42.3%, and 58.3%, respectively. After adjustment for sociodemographic determinants, the prevalence
ratios for high LDL-C were significantly higher for men, blacks, older subjects, and subjects with lower
levels of education. Low frequency of awareness, treatment, and uncontrolled values of LDL-C was
observed among men, mixed race and blacks, poorer, less educated, and those who did not have private
health insurance.
CONCLUSIONS: The prevalence of high LDL-C was elevated in this Brazilian population, with low
rates of awareness, treatment and control, and remarkable socioeconomic disparity.
2016 National Lipid Association. All rights reserved. | pt_BR |
Affilliation | University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil | pt_BR |
Affilliation | University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil | pt_BR |
Affilliation | Federal University S.Joao Del Rei. São João Del Rei, BH, Brazil / Federal University Minas Gerais. Minas Gerais, BH, Brazil | pt_BR |
Affilliation | University of Sao Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil / University of Sao Paulo. Heart Institute. São Paulo, SP, Brazil | pt_BR |
Affilliation | Federal University Espirito Santo. Vitoria, ES, Brazil | pt_BR |
Affilliation | Federal University Bahia. Salvador, BA, Brazil | pt_BR |
Affilliation | Oswaldo Cruz Foundation. Rio de Janeiro, RJ, Brazil | pt_BR |
Affilliation | Federal University Bahia. Salvador, BA, Brazil | pt_BR |
Affilliation | Federal University Espirito Santo. Vitoria, ES, Brazil | pt_BR |
Affilliation | Oswaldo Cruz Foundation. Rio de Janeiro, RJ, Brazil | pt_BR |
Affilliation | Federal University Rio Grande do Sul. Department of Preventive Medicine. Porto Alegre, RGS, Brasil | pt_BR |
Affilliation | Federal University of Minas Gerais. Department of Internal Medicine. Minas Gerais, BH, Brazil | pt_BR |
Affilliation | Federal University Rio Grande do Sul. Department of Preventive Medicine. Porto Alegre, RGS, Brasil | pt_BR |
Affilliation | University of São Paulo. Hospital Universitario. Center for Clinical and Epidemiologic Research. São Paulo, SP, Brazil | pt_BR |
Subject | Dyslipidemia | pt_BR |
Subject | Statins | pt_BR |
Subject | Coronary heart disease | pt_BR |
Subject | Epidemiology | pt_BR |
Subject | Risk factors | pt_BR |