Author | Abreu, Adriana Vieira de | |
Author | Campbell, Robert A. | |
Author | Weyrich, Andrew S. | |
Author | Zimmerman, Guy A. | |
Access date | 2017-11-01T10:55:11Z | |
Available date | 2017-11-01T10:55:11Z | |
Document date | 2012 | |
Citation | ABREU, Adriana Vieira de; et al. Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum. Semin Immunopathol., v.34, n.1, p.5-30, Jan. 2012. | pt_BR |
ISSN | 1863-2297 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/23014 | |
Language | eng | pt_BR |
Publisher | Springer Verlag (Germany) | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Plaquetas | pt_BR |
Subject in Portuguese | Inflamação | pt_BR |
Subject in Portuguese | Imunidade Inata | pt_BR |
Subject in Portuguese | Imunidade Adaptativa | pt_BR |
Subject in Portuguese | Infecção | pt_BR |
Subject in Portuguese | defesa do hospedeiro | pt_BR |
Title | Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum | pt_BR |
Type | Article | pt_BR |
DOI | 10.1007/s00281-011-0286-4 | |
Abstract | Platelets are chief effector cells in hemostasis. In addition, however, their specializations include activities and intercellular interactions that make them key effectors in inflammation and in the continuum of innate and adaptive immunity. This review focuses on the immune features of human platelets and platelets from experimental animals and on interactions between inflammatory, immune, and hemostatic activities of these anucleate but complex and versatile cells. The experimental findings and evidence for physiologic immune functions include previously unrecognized biologic characteristics of platelets and are paralleled by new evidence for unique roles of platelets in inflammatory, immune, and thrombotic diseases. | pt_BR |
Affilliation | University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA. | pt_BR |
Affilliation | University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA. | pt_BR |
Affilliation | University of Utah School of Medicine. Department of Medicine. Salt Lake City, Utah, USA. | pt_BR |
Subject | Platelets | pt_BR |
Subject | Inflammation | pt_BR |
Subject | Innate immunity | pt_BR |
Subject | Adaptive immunity | pt_BR |
Subject | Infection | pt_BR |
Subject | Host defense | pt_BR |
e-ISSN | 1863-2300 | |
Embargo date | 2030-01-01 | |