Author | Andrade, Carine de Sousa | |
Author | Ribeiro, Guilherme de Sousa | |
Author | Santos, Carlos Antonio Souza Teles | |
Author | Neves, Raimundo Celestino Silva | |
Author | Moreira Junior, Edson Duarte | |
Access date | 2018-02-20T12:54:05Z | |
Available date | 2018-02-20T12:54:05Z | |
Document date | 2017 | |
Citation | ANDRADE, C. S. et al. Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil. BMJ Open, v. 7, e018094, 2017. | pt_BR |
ISSN | 2044-6055 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/24876 | |
Sponsorship | The Brazilian Study of Diabetes Control was funded by Pfizer, Brazil. CSA received scholarship from the Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. GSR and EDM received scholarships from the National Council for Scientific and Technological
Development (CNPq). | pt_BR |
Language | eng | pt_BR |
Publisher | BMJ Publishing Group | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Controle glicêmico | pt_BR |
Subject in Portuguese | Epidemiologia | pt_BR |
Subject in Portuguese | Hemoglobina glicada | pt_BR |
Subject in Portuguese | Diabetes tipo 1 | pt_BR |
Title | Factors associated with high levels of glycated haemoglobin in patients with type 1 diabetes: a multicentre study in Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1136/bmjopen-2017-018094 | |
Abstract | Long-term complications of type 1 diabetes mellitus (DM1) can be prevented with adequate glycaemic control. However, high levels of glycated haemoglobin (HbA1c) occur in 60%-90% of the patients with DM1. Thus, we aimed to investigate the role of sociodemographic, behavioural and clinical factors on the HbA1c levels of patients with DM1 in Brazil. Design, setting and participants A cross-sectional study
was conducted in ambulatory patients with DM1 aged
≥18 years from 10 Brazilian cities. Sociodemographic,
behavioural and clinical data were obtained through
interviews.
Main outcome measures HbA1c level was measured by
liquid chromatography. Hierarchical multiple variable linear
regression models were used to identify factors correlated
with high levels of HbA1c.
Results Of 979 patients with DM1, 63.8% were women,
and the mean age was 40 (SD 14.6) years. The mean
HbA1c level was 9.4% (SD 2.2%), and 89.6% of the
patients had HbA1c ≥7.0%. Factors independently
correlated with increased HbA1c levels included: lower
education, non-participation in diabetes classes/lecture
during the year before, having a self-perception of poor
adherence to diet and insulin, not having private medical
care and not measuring the HbA1c levels in the prior
year. Of note, poor adherence to diet and insulin were the
independent factors most strongly associated with high
levels of HbA1c (mean increment in HbA1c levels of 0.88%
and 1.25%, respectively).
Conclusion Poor glycaemic control, which is common
among Brazilian patients with DM1, is associated with
lower education, self-perception of insufficient adherence
to diet and insulin and inadequate monitoring of HbA1c
levels. Specific actions, particularly those targeting
improving adherence to diet and insulin, may contribute to successful management of patients with DM1. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Escola de Nutrição. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / State University of Feira de Santana. Department of Exact Sciences. Feira de Santana, BA, Brazil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Charitable Works Foundation of Sister Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Subject | Glycaemic control | pt_BR |
Subject | Epidemiology | pt_BR |
Subject | Glycated Haemoglobin | pt_BR |
Subject | Type 1 diabetes | pt_BR |