Author | Luz, José Hugo Mendes | |
Author | Luz, Paula Mendes | |
Author | Bilhim, Tiago | |
Author | Martin, Henrique Salas | |
Author | Gouveia, Hugo Rodrigues | |
Author | Coimbra, Élia | |
Author | Gomes, Filipe Veloso | |
Author | Souza, Roberto Romulo | |
Author | Faria, Igor Murad | |
Author | de Miranda, Tiago Nepomuceno | |
Access date | 2018-04-12T16:01:33Z | |
Available date | 2018-04-12T16:01:33Z | |
Document date | 2017 | |
Citation | LUZ, José Hugo Mendes, et al. Portal vein embolization with n-butylcyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients. Cancer Imaging, v. 17, n. 25, 2017. | pt_BR |
ISSN | 1470-7330 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/25819 | |
Language | eng | pt_BR |
Publisher | BioMed Central | pt_BR |
Rights | open access | pt_BR |
Title | Portal vein embolization with n-butyl-cyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients | pt_BR |
Type | Article | pt_BR |
DOI | 10.1186/s40644-017-0127-3 | |
Abstract | Purpose: To evaluate the efficacy of portal vein embolization (PVE) with n-Butyl-cyanoacrylate (NBCA) through
an ipsilateral approach before major hepatectomy. Secondary end-points were PVE safety, liver resection and
patient outcome. Methods: Over a 5-year period 50 non-cirrhotic consecutive patients were included with primary or secondary liver cancer treatable by hepatectomy with a liver remnant (FLR) volume less than 25% or less than 40% in diseased livers. Results: There were 37 men and 13 women with a mean age of 57 years. Colorectal liver metastases were the most frequent tumor and patients were previously exposed to chemotherapy. FLR increased from 422 ml to 629 ml (P < 0.001) after PVE, corresponding to anincrease of 52%. The FLR ratio increased from 29.6% to 42.3% (P < 0.001). Kinetic growth rate was 2.98%/week. A negative association was observed between increase in the FLR and FLR ratio and FLR volume before PVE (P = 0.002). In 31 patients hepatectomy was accomplished and only one patient presented with liver insufficiency within 30 days after surgery. Conclusions: PVE with NBCA through an ipsilateral puncture is effective before major hepatectomy. Meticulous attention is needed especially near the end of the embolization procedure to avoid complications. | pt_BR |
Affilliation | Department of Interventional Radiology, Radiology Division, National Cancer Institute, INCA, Rio de Janeiro, Brazil | pt_BR |
Affilliation | Fundação Oswaldo Cruz.Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Department of Interventional Radiology, Centro Hepato-Bilio-Pancreático e de Transplantação.Hospital Curry Cabral, CHLC, Lisbon, Portugal | pt_BR |
Affilliation | Department of Interventional Radiology, Radiology Division, National Cancer Institute, INCA, Rio de Janeiro, Brazil | pt_BR |
Affilliation | Department of Interventional Radiology, Radiology Division, National Cancer Institute, INCA, Rio de Janeiro, Brazil | pt_BR |
Affilliation | Department of Interventional Radiology, Centro Hepato-Bilio-Pancreático e de Transplantação.Hospital Curry Cabral, CHLC, Lisbon, Portugal | pt_BR |
Affilliation | Department of Interventional Radiology, Centro Hepato-Bilio-Pancreático e de Transplantação.Hospital Curry Cabral, CHLC, Lisbon, Portugal | pt_BR |
Affilliation | Department of Interventional Radiology, Radiology Division, National Cancer Institute, INCA, Rio de Janeiro, Brazil | pt_BR |
Affilliation | Department of Interventional Radiology, Radiology Division, National Cancer Institute, INCA, Rio de Janeiro, Brazil | pt_BR |
Affilliation | Department of Interventional Radiology, Radiology Division, National Cancer Institute, INCA, Rio de Janeiro, Brazil | pt_BR |
Subject | Portal Vein | pt_BR |
Subject | Embolization | pt_BR |
Subject | Future liver remnant | pt_BR |
Subject | Extended hepatectomy | pt_BR |
Subject | Hepatic Insufficiency | pt_BR |
DeCS | Veia Porta | pt_BR |
DeCS | Insuficiência Hepática | pt_BR |