Author | Rocha, Leonardo de Souza | |
Author | Falqueto, Aloisio | |
Author | Santos, Claudinei Biral dos | |
Author | Grimaldi Jr., Gabriel | |
Author | Cupolillo, Elisa | |
Access date | 2018-04-19T16:51:20Z | |
Available date | 2018-04-19T16:51:20Z | |
Document date | 2010 | |
Citation | ROCHA, Leonardo de Souza; et al. Possible Implication of the Genetic Composition of the Lutzomyia longipalpis (Diptera: Psychodidae) Populations in the Epidemiology of the Visceral Leishmaniasis. Journal of Medical Entomology, v.48, n.5, p.1016-1022, 2010. | pt_BR |
ISSN | 0022-2585 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/25964 | |
Language | eng | pt_BR |
Publisher | Entomological Society of America | pt_BR |
Rights | restricted access | |
Subject in Portuguese | Lutzomyia longipalpis | pt_BR |
Subject in Portuguese | Leishmania infantum | pt_BR |
Subject in Portuguese | Genética populacional | pt_BR |
Subject in Portuguese | Leishmaniose visceral | pt_BR |
Subject in Portuguese | cytochrome b | pt_BR |
Title | Possible Implication of the Genetic Composition of the Lutzomyia longipalpis (Diptera: Psychodidae) Populations in the Epidemiology of the Visceral Leishmaniasis | pt_BR |
Type | Article | pt_BR |
DOI | 10.1603/ME10249 | |
Abstract | Lutzomyia longipalpis (Diptera: Psychodidae) is the principal vector of American
visceral leishmaniasis. Several studies have indicated that the Lu. longipalpis population structure is
complex. It has been suggested that genetic divergence caused by genetic drift, selection, or both may
affect the vectorial capacity of Lu. longipalpis. However, it remains unclear whether genetic differences
among Lu. longipalpis populations are directly implicated in the transmission features of visceral
leishmaniasis.Weevaluated the genetic composition and the patterns of genetic differentiation among
Lu. longipalpis populations collected from regions with different patterns of transmission of visceral
leishmaniasis by analyzing the sequence variation in the mitochondrial cytochrome b gene. Furthermore,
we investigated the temporal distribution of haplotypes and compared our results with those
obtained in a previous study. Our data indicate that there are differences in the haplotype composition
and that there has been signiÞcant differentiation between the analyzed populations. Our results
reveal that measures used to control visceral leishmaniasis might have inßuenced the genetic composition
of the vector population. This Þnding raises important questions concerning the epidemiology
of visceral leishmaniasis, because these differences in the genetic structures among populations of Lu.
longipalpis may have implications with respect to their efÞciency as vectors for visceral leishmaniasis. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pequisas em Leishmanioses. Rio de Janeiro, RJ. Brasil / Centro Universitário do Espírito Santo. Colatina, ES, Brasil. | pt_BR |
Affilliation | Universidade do Espírito Santo. Unidade de Medicina Tropical. Vitória, ES, Brasil. | pt_BR |
Affilliation | Universidade do Espírito Santo. Unidade de Medicina Tropical. Vitória, ES, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pequisas em Leishmanioses. Rio de Janeiro, RJ. Brasil, | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pequisas em Leishmanioses. Rio de Janeiro, RJ. Brasil, | pt_BR |
Subject | Lutzomyia longipalpis | pt_BR |
Subject | visceral leishmaniasis | pt_BR |
Subject | Leishmania infantum | pt_BR |
Subject | cytochrome b | pt_BR |
Subject | population genetics | pt_BR |
e-ISSN | 1938-2928 | |
Embargo date | 2030-01-01 | |