Author | Moraes, Diego N. | |
Author | Nascimento, Bruno Ramos | |
Author | Beaton, Andrea Z. | |
Author | Soliman, Elsayed Z. | |
Author | Costa, Maria Fernanda Lima | |
Author | Reis, Rodrigo Citton Padilha dos | |
Author | Ribeiro, Antonio Luiz Pinho | |
Access date | 2018-06-13T16:31:20Z | |
Available date | 2018-06-13T16:31:20Z | |
Document date | 2018 | |
Citation | MORAES, Diego N et al. Value of the Electrocardiographic (P Wave, T Wave, QRS) Axis as a Predictor of Mortality in 14 Years in a Population With a High Prevalence of Chagas Disease from the Bambuí Cohort Study of Aging. Am J Cardiol., v. 121, n. 3, p. 364-369, 2018. | pt_BR |
ISSN | 0002-9149 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/26873 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Idosos | pt_BR |
Subject in Portuguese | Doença de chagas | pt_BR |
Subject in Portuguese | electrocardiograma | pt_BR |
Title | Value of the Electrocardiographic (P Wave, T Wave, QRS) Axis as a Predictor of Mortality in 14 Years in a Population With a High Prevalence of Chagas Disease from the Bambuí Cohort Study of Aging | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.amjcard.2017.10.020 | |
Abstract | We sought to investigate the prognostic value of the electrocardiogram (ECG) electrical axes (P wave, T wave and QRS) as predictors of mortality in the 14-year follow-up of the prospective cohort of all residents ≥60 years living in the southeastern Brazilian city of Bambuí, a population with high prevalence of Chagas disease (ChD). Baseline ECG axes were automatically measured with normal values defined as follows: P-wave axis 0° to 75°, QRS axis -30° to 90°, and T axis 15° to 75°. Participants underwent annual follow-up visits and death was verified using death certificates. Cox proportional hazards regression was used to assess the prognostic value of ECG axes for all-cause mortality, after adjustment for potential confounders. From 1,742 qualifying residents, 1,462 were enrolled, of whom 557 (38.1%) had ChD. Mortality rate was 51.9%. In multivariable adjusted models, abnormal P-wave axis was associated with a 48% (hazard ratio [HR] = 1.48 [95% confidence interval (CI) 1.16-1.88]) increased mortality risk in patients with ChD and 43% (HR = 1.43 [CI 1.13-1.81]) in patients without ChD. Abnormal QRS axis was associated with a 34% (HR = 1.34 [CI 1.04-1.73]) increased mortality risk in patients with ChD, but not in individuals without ChD. Similarly, in the ChD group, abnormal T-wave axis was associated with a 35% (HR = 1.35 [CI 1.07-1.71]) increased mortality, but not in patients without ChD. In conclusion, abnormal P-wave, QRS, and T-wave axes were associated with increased all-cause mortality in patients with ChD. Abnormal P-wave axis was associated with mortality also among those without ChD, being the strongest predictor among ECG variables. | pt_BR |
Affilliation | Universidade Federal de Minas Gerais. Hospital das Clínicas. Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Universidade Federal de Minas Gerais. Hospital das Clínicas. Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Hospital das Clínicas. Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Clínica Médica. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Cardiology Department. Children's National Health System. Washington, District of Columbia. | pt_BR |
Affilliation | Department of Epidemiology & Prevention. Wake Forest School of Medicine. Winston-Salem, North Carolina. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisas René Rachou. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Saúde Pública. Belo Horizonte, MG, Brazil. | pt_BR |
Affilliation | Universidade Federal de Minas Gerais. Hospital das Clínicas. Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Hospital das Clínicas. Serviço de Cardiologia e Cirurgia Cardiovascular e Centro de Telessaúde. Belo Horizonte, MG, Brazil/Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Clínica Médica. Belo Horizonte, MG, Brazil. | pt_BR |
Subject | aging | pt_BR |
Subject | Chagas Disease | pt_BR |
Subject | electrocardiogram | pt_BR |
Embargo date | 2020-01-01 | |
xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |