Author | Moreira Júnior, Edson Duarte | |
Author | Souza, Verena Maria Mendes de | |
Author | Sreenivasan, Meera | |
Author | Nascimento, Eliane Góes | |
Author | Pontes-de-Carvalho, Lain Carlos | |
Access date | 2011-10-26T20:50:17Z | |
Available date | 2011-10-26T20:50:17Z | |
Document date | 2002 | |
Citation | MOREIRA JUNIOR, E.D. et al. Assessment of an optimized dog-culling program in the dynamics of canine Leishmania transmission. Veterinary Parasitology, v. 122, n. 4, p. 245-252, aug. 2004. | pt_BR |
ISSN | 0304-4017 | |
URI | https://www.arca.fiocruz.br/handle/icict/3268 | |
Language | eng | pt_BR |
Rights | open access | |
Title | Assessment of an optimized dog-culling program in the dynamics of canine Leishmania transmission. | pt_BR |
Type | Article | pt_BR |
DOI | doi:10.1016/j.vetpar.2004.05.019 | |
Abstract | In Brazil, zoonotic visceral leishmaniasis (ZVL) control programs based on the mass elimination
of seropositive dogs have failed to reduce the number of leishmaniasis cases. However, these
programs have been done under sub-optimal conditions. We studied a cohort of dogs in an urban
area in Brazil to determine, whether a dog-culling program optimized with: (i) replacement of
a relatively low-sensitivity indirect immune-fluorescent test on blood eluate by a more sensitive
enzyme-linked immunosorbent assay on serum blood samples; (ii) shortening of the time interval
from serodiagnosis to removal of dogs; (iii) screening a high proportion of the dog population could
reduce the incidence of canine Leishmania infection (CLI). The study ran from December 1997
to July 2000, with four follow-up assessments performed at approximately 8-month intervals. All
dogs seropositive for anti-Leishmania antibodies were promptly eliminated. A large number of new
dogs immigrated to the study area throughout the study period. They comprised 43.8–49.8% of
the cohort at each follow-up assessment, and upto 15% of them already had Leishmania infection.
Overall, 42 news cases of CLI were identified, for a crude incidence rate of 11.8 cases per 100
dog-years (95% CI 8.6–15.6). In the first, second, third and fourth follow-up assessments the incidence
rates were 8.2 (95% CI 3.0–17.9), 12.2 (95% CI 6.3–21.2), 16.4 (95% CI 8.5–28.6) and 13.6 | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | University of California at Berkeley. School of Public Health. Berkeley, USA | pt_BR |
Affilliation | Secretaria da Saúde do Estado da Bahia. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
DeCS | Anticorpos Antiprotozoários | pt_BR |
DeCS | Estudos de Coortes | pt_BR |
DeCS | Reservatórios de Doenças | pt_BR |
DeCS | Doenças do Cão | pt_BR |
DeCS | ELISA | pt_BR |
DeCS | Leishmania | pt_BR |
DeCS | Leishmaniose Visceral | pt_BR |
DeCS | Controle da População | pt_BR |
DeCS | Fatores de Tempo | pt_BR |
DeCS | Zoonoses | pt_BR |
DeCS | Animais | pt_BR |
DeCS | Cães | pt_BR |