Author | Barral Netto, Manoel | pt_BR |
Author | Roters, Silene B. | pt_BR |
Author | Sherlock, Ítalo Rodrigues de Araújo | pt_BR |
Author | Reed, S. G. | pt_BR |
Access date | 2019-06-19T17:14:47Z | |
Available date | 2019-06-19T17:14:47Z | |
Document date | 1987 | |
Citation | BARRAL NETTO, Manoel et al. Destruction of Leishmania Mexicana Amazonensis promastigotes by normal human serum. American Journal of Tropical Medicine and Hygiene, v. 37, n. 1, p. 53-56, 1987. | pt_BR |
ISSN | 0002-9637 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/33592 | |
Abstract in Portuguese | Fresh normal human serum was observed to have a lethal effect on Leishmania mexicana amazonensis promastigotes obtained from laboratory-bred Lutzomyia longipalpis or on promastigotes grown in liquid culture medium, inoculated with the same isolates. Heat inactivation abolished the Leishmania lytic activity from the sera. Resistance of culture promastigotes to lysis by normal human serum was investigated in three isolates of L. m. amazonensis. Development of resistance (up to 7%) was found in only one isolate, obtained from the bone marrow in a human case of visceral leishmaniasis. | |
Sponsorship | Brazilian National research Council (CNPq-40.3683/82-PIDE V) and United States Public Health Service grant 16282. | pt_BR |
Language | eng | pt_BR |
Publisher | American Society of Tropical Medicine and Hygiene | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Leishmania mexicana | pt_BR |
Subject in Portuguese | Lutzomyia | pt_BR |
Subject in Portuguese | Leishmania | pt_BR |
Subject in Portuguese | Soro | pt_BR |
Title | Destruction of Leishmania Mexicana Amazonensis promastigotes by normal human serum | pt_BR |
Type | Article | pt_BR |
DOI | 10.4269/ajtmh.1987.37.53 | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Cornell University. Weill Cornell Medicine. New York, NY, United States. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Cornell University. Weill Cornell Medicine. New York, NY, United States. | pt_BR |
Subject | Mexican leishmania | en |
Subject | Lutzomyia | en |
Subject | Leishmania | en |
Subject | Serum | en |
Embargo date | 2022-01-06 | |