| Author | Lewis-Ximenez, Lia L. | |
| Author | Ó, Kycia M. R. do | |
| Author | Ginuino, Cleber F. | |
| Author | Silva, Jucimara C. | |
| Author | Schatzmayr, Herrmann G. | |
| Author | Stuver, Sherri | |
| Author | Yoshida, Clara F. T. | |
| Access date | 2019-07-16T17:13:32Z | |
| Available date | 2019-07-16T17:13:32Z | |
| Document date | 2002 | |
| Citation | LEWIS-XIMENES, Lia L. et al. Risk factors for hepatitis B virus infection in Rio de Janeiro, Brazil. BMC Public Health, n. 2, p. 1-5, 2002. | pt_BR |
| ISSN | 1471-2458 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/34165 | |
| Language | eng | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Vírus da Hepatite B | pt_BR |
| Subject in Portuguese | Fatores de risco | pt_BR |
| Subject in Portuguese | Infecção | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Title | Risk factors for hepatitis B virus infection in Rio de Janeiro, Brazil | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1186/1471-2458-2-26 | pt_BR |
| Abstract | Background: Despite international efforts to prevent hepatitis B virus (HBV) infection through
global vaccination programs, new cases are still being reported throughout the world.
Methods: To supply data that might assist in improving preventive measures and national
surveillance for HBV infection, a cross-sectional study was conducted among individuals referred
to the Brazilian National Reference Center for Viral Hepatitis (Rio de Janeiro) during a two-year
period. Reported risk factors among infected subjects ("HBV-positive") were compared to those
of subjects never exposed ("HBV-negative") to HBV. Two subgroups were further identified within
the HBV-positive group, "acute" infection and "non-acute" infection.
Results: A total of 1,539 subjects were tested for HBV, of which 616 were HBV-positive (79 acute
infection and 537 non-acute infection). HBV-positive subjects were more likely to be of male
gender (63% versus 47%); and to report multiple sexual partners (12% versus 6%) and illicit drug
use (IDU and/or intranasal cocaine use) (6% versus 3%). Among the HBV-positive subgroups, age
differed significantly, with 48% being under 30 years of age in subjects acutely infected compared
to 17% in those with non-acute infection.
Conclusions: The association of multiple sexual partners with past HBV infection and the age
distribution of currently infected subjects suggest that sexual transmission played a major role in
the transmission of HBV in this study population. Thus, vaccination during adolescence should be
considered. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Centro de Referência Nacional para Hepatites Virais. Rio de Janeiro, RJ. Brasil / Harvard School of Public Health. Department of Epidemiology. Boston, MA, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Centro de Referência Nacional para Hepatites Virais. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Centro de Referência Nacional para Hepatites Virais. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Centro de Referência Nacional para Hepatites Virais. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Centro de Referência Nacional para Hepatites Virais. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Harvard School of Public Health. Department of Epidemiology. Boston, MA, USA. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Centro de Referência Nacional para Hepatites Virais. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Subject | Risk factors | pt_BR |
| Subject | Hepatitis B virus | pt_BR |
| Subject | Infection | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
