Advisor | Struchiner, Claudio José | |
Advisor | Vilela, Daniel Antunes Maciel | |
Author | Fernández, Hugo Roberto | |
Access date | 2020-03-06T13:58:09Z | |
Available date | 2020-03-06T13:58:09Z | |
Document date | 2015 | |
Citation | FERNÁNDEZ, Hugo Roberto. Impacto de la diabetes en la dinámica de la transmisíon de la tuberculosis en Argentina. 2015. ix,61 f. Dissertação (Mestrado em Epidemiologia em Saúde Pública) - Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, 2015. | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/40239 | |
Language | por | pt_BR |
Rights | open access | pt_BR |
Title | Impacto de la diabetes en la dinámica de la transmisíon de la tuberculosis en Argentina | pt_BR |
Alternative title | Impact of diabetes on the transmission dynamics of tuberculosis in Argentina | pt_BR |
Type | Dissertation | pt_BR |
Defense date | 2015 | |
Departament | Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz. | pt_BR |
Defense Institution | Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública Sergio Arouca. | pt_BR |
Degree level | Mestrado Acadêmico | pt_BR |
Place of Defense | Rio de Janeiro/RJ | pt_BR |
Program | Programa de Pós-Graduação em Epidemiologia em Saúde Pública | pt_BR |
Abstract | The link between Diabetes and Tuberculosis has been recognized for long time. In recent decades acquired epidemiological importance in light of the expansion of the epidemic of type 2 diabetes mellitus in TB-endemic settings. The coexistence of diabetes and tuberculosis could have serious implications on TB control in many developing countries and be the next challenge for the global control of tuberculosis. In this context a better understanding of the interaction between the two diseases will allow better tools to address their control. Mathematical models are tools that have played a key role in strategies for TB control and the establishment of intermediate targets for intervention programs. This work presents a model, which includes the main components of the dynamics of tuberculosis and evaluates the dynamics for diabetes to change this behavior, worsening the situation of tuberculosis. A deterministic population-based model is proposed to analyze the impact of diabetes on the dynamics and treatment of Tuberculosis. The model calibrated with data estimated by WHO TB allowed projecting various scenarios for Argentina, generated from the evidence of interaction between the two conditions and intervention measures. The results are consistent with the international literature as evidence of a negative impact of the increase in diabetes in the situation of tuberculosis and its control. | pt_BR |
xmlui.metadata.dc.description.abstractes | The link between Diabetes and Tuberculosis has been recognized for long time. In recent
decades acquired epidemiological importance in light of the expansion of the epidemic
of type 2 diabetes mellitus in TB-endemic settings. The coexistence of diabetes and
tuberculosis could have serious implications on TB control in many developing countries
and be the next challenge for the global control of tuberculosis. In this context a better
understanding of the interaction between the two diseases will allow better tools to
address their control. Mathematical models are tools that have played a key role in
strategies for TB control and the establishment of intermediate targets for intervention
programs. This work presents a model, which includes the main components of the
dynamics of tuberculosis and evaluates the dynamics for diabetes to change this behavior,
worsening the situation of tuberculosis. A deterministic population-based model is
proposed to analyze the impact of diabetes on the dynamics and treatment of
Tuberculosis. The model calibrated with data estimated by WHO TB allowed projecting
various scenarios for Argentina, generated from the evidence of interaction between the
two conditions and intervention measures. The results are consistent with the international
literature as evidence of a negative impact of the increase in diabetes in the situation of
tuberculosis and its control. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Tuberculosis | pt_BR |
Subject | Diabetes | pt_BR |
Subject | Mathematical Models | pt_BR |
Subject | Numerical Simulation | pt_BR |
Subject | Intervention | pt_BR |
Subject | Sensitivity Analysis | pt_BR |
Subject in Spanish | Modelos Matemáticos | pt_BR |
Subject in Spanish | Simulación Numérica | pt_BR |
Subject in Spanish | Declaraciones | pt_BR |
Subject in Spanish | Análisis de Sensibilidad | pt_BR |
Subject in Spanish | Tuberculosis | pt_BR |
Subject in Spanish | Diabetes | pt_BR |
DeCS | Diabetes Mellitus Tipo 2 | pt_BR |
DeCS | Tuberculose | pt_BR |
DeCS | Modelos Matemáticos | pt_BR |
DeCS | Prevalência | pt_BR |
DeCS | Incidência | pt_BR |
DeCS | Estudos de Intervenção | pt_BR |
DeCS | Argentina | pt_BR |