Author | Rodrigues, Marcio Lourenço | |
Author | Nosanchuk, Joshua D. | |
Access date | 2020-04-28T22:43:08Z | |
Available date | 2020-04-28T22:43:08Z | |
Document date | 2020 | |
Citation | RODRIGUES, Marcio Lourenço et al. Fungal diseases as neglected pathogens: A wake-up call to public health officials. PLoS Neglected Tropical Diseases, v. 14, n. 2, p. 1-9, 2020. | pt_BR |
ISSN | 1935-2735 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/41026 | |
Language | por | pt_BR |
Publisher | Public Library of Science | pt_BR |
Rights | open access | pt_BR |
Title | Fungal diseases as neglected pathogens: A wake-up call to public health officials | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal.pntd.0007964 | |
Abstract | Human fungal diseases differ fundamentally from other infections in diverse ways. As eukaryotic pathogens, fungi share many similarities with their host cells, which impairs the development of antifungal compounds. Fungal tropism is highly variable, as pathogens infect a wide range of cell types. A single fungal pathogen can infect multiple tissues in the same patient (depending on the host’s immunological status) and can undergo morphogenic shifts during infection. Fungi are still underappreciated as major pathogens by both the public and public health officials. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Department of Medicine (Division of Infectious Diseases) and Department of Microbiology and Immunology. Albert Einstein College of Medicine. New York, NY, USA. | pt_BR |
Subject | Fungal Diseases | pt_BR |
Subject | Neglected Diseases | pt_BR |
Subject | Public Health | pt_BR |
Subject in Spanish | Enfermedades Desatendidas | pt_BR |
Subject in Spanish | Salud Pública | pt_BR |
DeCS | Doenças fúngicas | pt_BR |
DeCS | Saúde Pública | pt_BR |
DeCS | Doenças Negligenciadas | pt_BR |