Author | Angelo, Jussara R. | |
Author | Fuller, Trevon L. | |
Author | Leandro, Bianca B. S. | |
Author | Praça, Heitor L. F. | |
Author | Marques, Renata D. | |
Author | Ferreira, João M. C. | |
Author | Pupe, Camila C. B. | |
Author | Perez, Olívia C. | |
Author | Nielsen-Saines, Karin | |
Author | Nascimento, Osvaldo J. M. | |
Author | Sabroza, Paulo C. | |
Access date | 2020-06-04T19:13:45Z | |
Available date | 2020-06-04T19:13:45Z | |
Document date | 2020 | |
Citation | ANGELO, Jussara R. et al. Neurological complications associated with emerging viruses in Brazil. International Journal of Gynecology and Obstetrics, v. 148. suppl. 2, p. 70-75, 2020. | pt_BR |
ISSN | 0020-7292 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/41537 | |
Language | eng | pt_BR |
Publisher | International Federation of Gynaecology and Obstetrics | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Arbovirus | pt_BR |
Subject in Portuguese | Síndrome de Guillain-Barré | pt_BR |
Subject in Portuguese | Influenza Humana | pt_BR |
Subject in Portuguese | Polineuropatias | pt_BR |
Subject in Portuguese | Hospitais Públicos | pt_BR |
Subject in Portuguese | Vigilância de Evento Sentinela | pt_BR |
Title | Neurological complications associated with emerging viruses in Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1002/ijgo.13050 | |
Abstract | Objective: To test the hypotheses that emerging viruses are associated with neurological hospitalizations and that statistical models can be used to predict neurological sequelae from viral infections. Methods: An ecological study was carried out to observe time trends in the number of hospitalizations with inflammatory polyneuropathy and Guillain-Barré syndrome (GBS) in the state of Rio de Janeiro from 1997 to 2017. Increases in GBS from month to month were assessed using a Farrington test. In addition, a cross-sectional study was conducted analyzing 50 adults hospitalized for inflammatory polyneuropathies from 2015 to 2017. The extent to which Zika virus symptoms explained GBS hospitalizations was evaluated using a calibration test. Results: There were significant increases (Farrington test, P<0.001) in the incidence of GBS following the introduction of influenza A/H1N1 in 2009, dengue virus type 4 in 2013, and Zika virus in 2015. Of 50 patients hospitalized, 14 (28.0%) were diagnosed with arboviruses, 9 (18.0%) with other viruses, and the remainder with other causes of such neuropathies. Statistical models based on cases of emerging viruses accurately predicted neurological sequelae, such as GBS. Conclusion: The introduction of novel viruses increases the incidence of inflammatory neuropathies. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | University of California Los Angeles. Institute of the Environment and Sustainability. Los Angeles, CA, USA. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Politécnica de Saúde Joaquim Venâncio. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal Fluminense. Departamento de Neurologia. Niterói, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal Fluminense. Departamento de Neurologia. Niterói, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Piauí. Departamento de Ciência Política. Teresina, PI, Brasil. | pt_BR |
Affilliation | UCLA School of Medicine. Los Angeles, CA, USA. | pt_BR |
Affilliation | Universidade Federal Fluminense. Departamento de Neurologia. Niterói, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Arboviruses | pt_BR |
Subject | Guillain-Barre Syndrome | pt_BR |
Subject | Human Influenza | pt_BR |
Subject | Peripheral Nervous System Diseases | pt_BR |
Subject | Polyneuropathies | pt_BR |
Subject | Public Hospitals | pt_BR |
Subject | Sentinel Surveillance | pt_BR |
DeCS | Arboviruses | pt_BR |
DeCS | Guillain-Barre Syndrome | pt_BR |
DeCS | Influenza, Human | pt_BR |
DeCS | Hospitals, Public | pt_BR |
DeCS | Polyneuropathies | pt_BR |
DeCS | Sentinel Surveillance | pt_BR |