Author | Hamer, Sarah A. | |
Author | Corrêa, Alex Pauvolid | |
Author | Zecca, Italo B. | |
Author | Davila, Edward | |
Author | Auckland, Lisa A. | |
Author | Roundy, Christopher M. | |
Author | Tang, Wendy | |
Author | Torchetti, Mia Kim | |
Author | Killian, Mary Lea | |
Author | Jenkins-Moore, Melinda | |
Author | Mozingo, Katie | |
Author | Akpalu, Yao | |
Author | Ghai, Ria R. | |
Author | Spengler, Jessica R. | |
Author | Behravesh, Casey Barton | |
Author | Fischer, Rebecca S. B. | |
Author | Hamer, Gabriel L. | |
Access date | 2022-01-13T14:30:28Z | |
Available date | 2022-01-13T14:30:28Z | |
Document date | 2021 | |
Citation | HAMER, Sarah A. et al. SARS-CoV-2 Infections and Viral Isolations among Serially Tested Cats and Dogs in Households with Infected Owners in Texas, USA. Viruses, v. 13, 938, p. 1-16, May 2021. | pt_BR |
ISSN | 1999-4915 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/50749 | |
Language | eng | pt_BR |
Publisher | MDPI | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | SARS-CoV-2 | pt_BR |
Subject in Portuguese | Gatos | pt_BR |
Subject in Portuguese | Cães | pt_BR |
Subject in Portuguese | Zoonose reversa | pt_BR |
Subject in Portuguese | Isolamento de vírus | pt_BR |
Subject in Portuguese | Anticorpos neutralizantes | pt_BR |
Subject in Portuguese | COVID-19 | pt_BR |
Title | SARS-CoV-2 Infections and Viral Isolations among Serially Tested Cats and Dogs in Households with Infected Owners in Texas, USA | pt_BR |
Type | Article | pt_BR |
DOI | 10.3390/v13050938 | |
Abstract | Understanding the ecological and epidemiological roles of pets in the transmission of
SARS-CoV-2 is critical for animal and human health, identifying household reservoirs, and predicting
the potential enzootic maintenance of the virus. We conducted a longitudinal household transmission
study of 76 dogs and cats living with at least one SARS-CoV-2-infected human in Texas and found
that 17 pets from 25.6% of 39 households met the national case definition for SARS-CoV-2 infections
in animals. This includes three out of seventeen (17.6%) cats and one out of fifty-nine (1.7%) dogs that
were positive by RT-PCR and sequencing, with the virus successfully isolated from the respiratory
swabs of one cat and one dog. Whole-genome sequences of SARS-CoV-2 obtained from all four
PCR-positive animals were unique variants grouping with genomes circulating among people with
COVID-19 in Texas. Re-sampling showed persistence of viral RNA for at least 25 d-post initial test.
Additionally, seven out of sixteen (43.8%) cats and seven out of fifty-nine (11.9%) dogs harbored
SARS-CoV-2 neutralizing antibodies upon initial sampling, with relatively stable or increasing titers
over the 2–3 months of follow-up and no evidence of seroreversion. The majority (82.4%) of infected
pets were asymptomatic. ‘Reverse zoonotic’ transmission of SARS-CoV-2 from infected people to
animals may occur more frequently than recognized. | pt_BR |
Affilliation | College of Veterinary Medicine and Biomedical Sciences, Texas A&M University. College Station, TX 77843, USA. | pt_BR |
Affilliation | College of Veterinary Medicine and Biomedical Sciences, Texas A&M University. College Station, TX 77843, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratório e do Sarampo / Fundação Oswaldo Cruz. Laboratório de Referência Nacional e Regional de SARS-CoV-2 - Laboratório de Referência nas Américas (OPAS/OMS). Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | College of Veterinary Medicine and Biomedical Sciences, Texas A&M University. College Station, TX 77843, USA. | pt_BR |
Affilliation | College of Veterinary Medicine and Biomedical Sciences, Texas A&M University. College Station, TX 77843, USA. | pt_BR |
Affilliation | College of Veterinary Medicine and Biomedical Sciences, Texas A&M University. College Station, TX 77843, USA. | pt_BR |
Affilliation | Department of Entomology, Texas A&M University and AgriLife Research. College Station, TX 77843, USA. | pt_BR |
Affilliation | Department of Entomology, Texas A&M University and AgriLife Research. College Station, TX 77843, USA. | pt_BR |
Affilliation | National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA 50010, USA. | pt_BR |
Affilliation | National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA 50010, USA. | pt_BR |
Affilliation | National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA 50010, USA. | pt_BR |
Affilliation | National Veterinary Services Laboratories, USDA APHIS VS. Ames, IA 50010, USA. | pt_BR |
Affilliation | Brazos County Health Department. Bryan, TX 77803, USA. | pt_BR |
Affilliation | National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA 30329, USA. | pt_BR |
Affilliation | National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA 30329, USA. | pt_BR |
Affilliation | National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention. Atlanta, GA 30329, USA. | pt_BR |
Affilliation | School of Public Health, Texas A&M University. College Station, TX 77843, USA. | pt_BR |
Affilliation | Department of Entomology, Texas A&M University and AgriLife Research. College Station, TX 77843, USA. | pt_BR |
Subject | SARS-CoV-2 | pt_BR |
Subject | Cats | pt_BR |
Subject | Dogs | pt_BR |
Subject | Reverse zoonosis | pt_BR |
Subject | Virus isolation | pt_BR |
Subject | Neutralizing antibodies | pt_BR |
Subject | COVID-19 | pt_BR |