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https://www.arca.fiocruz.br/handle/icict/56213
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ArtigoDireito Autoral
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- IOC - Artigos de Periódicos [12514]
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THE FIRST ITALIAN OUTBREAK OF SARS‐COV‐2 B.1.1.7 LINEAGE IN CORZANO, LOMBARDY
Autor(es)
Afiliação
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de MInas Gerais. Instituto de Ciências Biológicas. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.
Unit of Medical Statistics and Molecular Epidemiology, University Campus Bio‐Medico of Rome, Rome, Italy.
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil / Universidade Federal de MInas Gerais. Instituto de Ciências Biológicas. Laboratório de Genética Celular e Molecular. Belo Horizonte, MG, Brasil.
Unit of Medical Statistics and Molecular Epidemiology, University Campus Bio‐Medico of Rome, Rome, Italy.
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Section of Microbiology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Resumo em Inglês
In December 2020, Italy experienced the first case of severe acute respiratory syndrome
coronavirus‐2 (SARS‐CoV‐2) B.1.1.7 lineage. In January 2021, we identified 21 cases of
this variant in Corzano, defining the first outbreak of SARS‐CoV‐2 B.1.1.7 lineage in Italy.
The high transmissibility of the B.1.1.7 variant represented an important benefit for the
virus, which became rapidly dominant on the territory. Containment measures induced
the epidemic curve onto a decreasing trajectory underlining the importance of appropriate
control and surveillance for restraint of virus spread.
Highlights The first Italian outbreak of SARS‐CoV‐2 B.1.1.7 lineage occurred in
Lombardy in January 2021. The outbreak originated by a single introduction of the
B.1.1.7 lineage. The genomic sequencing revealed, for the first time, the presence of
the V551F mutation in the B.1.1.7 lineage in Italy. Surveillance, prompt sequencing
and tracing efforts were fundamental to identify and to quickly contain the outbreak.
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