Author | Leão-Buchir, Joelma | |
Author | Souza, Tugstênio Lima de | |
Author | Souza, Claudemir de | |
Author | Fávaro, Luís Fernando | |
Author | Brito, Patrícia Manuitt | |
Author | Carneiro, Milena Carvalho | |
Author | Marcon, Bruna Hilzendeger | |
Author | Esquivel, Luíse | |
Author | Ribeiro, Ciro Alberto de Oliveira | |
Author | Prodocimo, Maritana Mela | |
Access date | 2023-03-02T11:41:02Z | |
Available date | 2023-03-02T11:41:02Z | |
Document date | 2023 | |
Citation | LEÃO-BUCHIR, Joelma et al. BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure. Environmental Toxicology and Pharmacology, v. 97, p. 1–15, 2023. | en_US |
ISSN | 1872-7077 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/57170 | |
Language | por | en_US |
Publisher | Elsevier | en_US |
Rights | open access | en_US |
Title | BDE-99 (2,2′,4,4′,5 - pentain polybrominated diphenyl ether) induces toxic effects in Oreochromis niloticus after sub-chronic and oral exposure | en_US |
Type | Article | en_US |
DOI | 10.1016/j.etap.2022.104034 | |
Abstract | PBDEs are toxic, lipophilic, hydrophobic, and persistent artificial chemicals, characterized by high physical and chemical stability. Although PBDEs are known to disturb hormone signaling, many effects of 2,2′ ,4,4′ ,5 - pentain
polybrominated diphenyl ethers (BDE-99) in fish remain unclear. The current study investigates the effects of BDE-99 in Oreochromis niloticus where sixty-four juvenile fish were orally exposed to 0.294, 2.94, 29.4 ng g 1 of
BDE-99, every 10 days, during 80 days. The results showed histopathological findings in liver and kidney, increasing acetylcholinesterase activity in muscle, disturbs in the antioxidant system in liver and brain and decreasing the plasmatic levels of vitellogenin in females. According to multivariate analysis (IBR), the higher doses are related to the interaction of oxidative and non-oxidative enzymes. The present study provided evidence of deleterious effects after sub-chronic exposure of BDE 99 to O. niloticus, increasing the knowledge about its risk of exposure in fish. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. / Departamento de Toxicologia Molecular e Ambiente. Centro de Biotecnologia. Universidade Eduardo Mondlane. Maputo, Mozambique. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. | en_US |
Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Imunologia. São Paulo, SP, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. | en_US |
Affilliation | Estação de Piscicultura Panamá. Paulo Lopes, Brasil. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. | en_US |
Affilliation | Universidade Federal do Paraná. Departamento de Biologia Celular. Curitiba, PR, Brasil. | en_US |
Subject | Water Quality | en_US |
Subject | Biomarkers | en_US |
Subject | Polybrominated Diphenyl Ethers | en_US |
Subject | Brominated Flame Retardants | en_US |
Subject | Fresh Water | en_US |
Subject | Tilapia | en_US |
Subject in Spanish | Calidad del Agua | en_US |
Subject in Spanish | Éteres Difenilos Halogenados | en_US |
Subject in Spanish | Agua Dulce | en_US |
Subject in French | Qualité de l'eau | en_US |
Subject in French | Marqueurs biologiques | en_US |
Subject in French | Éthers de polyhalogénophényle | en_US |
Subject in French | Eau douce | en_US |
DeCS | Qualidade da Água | en_US |
DeCS | Biomarcadores | en_US |
DeCS | Éteres Difenil Halogenados | en_US |
DeCS | Água Doce | en_US |
DeCS | Tilápia | en_US |