Author | Zamith-Miranda, D. | |
Author | Nimrichter, L. | |
Author | Rodrigues, M. L. | |
Author | Nosanchuk, J. D. | |
Access date | 2023-07-13T23:55:23Z | |
Available date | 2023-07-13T23:55:23Z | |
Document date | 2018 | |
Citation | ZAMITH-MIRANDA, D. et al. Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host. Microbes and Infection, v. 20, n. 9-10, p. 501-501, 2018. | en_US |
ISSN | 1286-4579 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/59581 | |
Language | eng | en_US |
Publisher | Elsevier | en_US |
Rights | open access | en_US |
MeSH | Biological Transport | en_US |
MeSH | Cell Communication | en_US |
MeSH | Extracellular Vesicles | en_US |
MeSH | Fungal Proteins | en_US |
MeSH | Fungi | en_US |
MeSH | Host-Pathogen Interactions | en_US |
MeSH | Immune Evasion | en_US |
MeSH | Species Specificity | en_US |
Title | Fungal extracellular vesicles: modulating host–pathogen interactions by both the fungus and the host | en_US |
Type | Article | en_US |
DOI | 10.1016/J.MICINF.2018.01.011 | |
Abstract | The secretion of biomolecules by fungal cells occurs via the conventional export of signal peptide-coupled soluble molecules, but it also results from transport within extracellular vesicles (EV). During the last ten years since the description of this non-conventional secretion pathway, varied, interesting biological roles have been associated with EV release by fungi. The various organic molecules carried by these structures are involved in pathogenesis and immune evasion, and may be associated with cell-cell communication. In regards to host-pathogen interactions, EV roles are diverse and organism-specific, although some features seem to be conserved among the pathogenic fungal organisms studied to date. This review aims to highlight our current understanding of the biologically relevant findings regarding EV released by the pathogenic fungal organisms and describes our knowledge of the roles of EV in host-pathogen interactions. | en_US |
Affilliation | Department of Microbiology and Immunology. Albert Einstein College of Medicine. USA / Division of Infectious Diseases. Department of Medicine. Albert Einstein College of Medicine. USA. | en_US |
Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brazil. | en_US |
Affilliation | Department of Microbiology and Immunology. Albert Einstein College of Medicine. USA / Division of Infectious Diseases. Department of Medicine. Albert Einstein College of Medicine. USA. | en_US |
Affilliation | Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil. | en_US |
Subject | Fungus | en_US |
Subject | Extracellular vesicles | en_US |
Subject | Cryptococcus | en_US |
Subject | Histoplasma | en_US |
Subject | Paracoccidioides | en_US |
Subject | Candida | en_US |
Subject | pathogenesis | en_US |
e-ISSN | 1769-714X | |