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Autor | Krakhecke-Teixeira, Alessandra G. | |
Autor | Yamauchi, Danielle H. | |
Autor | Rossi, Alexsandra | |
Autor | Sousa, Herdson Renney de | |
Autor | Garces, Hans G. | |
Autor | Lucas Júnior, Joaquim | |
Autor | Santos Júnior, Antonio Oliveira dos | |
Autor | Felipe, Maria Sueli S. | |
Autor | Bagagli, Eduardo | |
Autor | Andrade Júnior, Heitor F. de | |
Autor | Teixeira, Marcus de M. | |
Fecha de acceso | 2023-08-23T23:02:26Z | |
Fecha de disponibilización | 2023-08-23T23:02:26Z | |
Fecha de publicación | 2022 | |
Referencia | KRAKHECKE-TEIXEIRA, Alessandra G. et al. Clinical and eco-epidemiological aspects of a novel hyperendemic area of Paracoccidioidomycosis in the Tocantins-Araguaia Basin (Northern Brazil), Caused by Paracoccidioides sp. Journal Fungi, [Basel], v. 8, n. 5, p.1-11, may 2022. | en_US |
ISSN | 2309-608X | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/60202 | |
Promoción | This study was supported by the Tocantins State Department of Science and Technology (SECT) and the Tocantins State Council for Science and Technology (CEPT) for fellowships and support of AGK in its doctoral work. The research was on the scientific collaboration agreement between FMT and IMTSP/USP and was partially supported by LIMHC/FMUSP. | en_US |
Idioma | eng | en_US |
Editor | MDPI | en_US |
Derechos de autor | open access | en_US |
MeSH | Paracoccidioidomicose | en_US |
Título | Clinical and eco-epidemiological aspects of a novel hyperendemic area of Paracoccidioidomycosis in the Tocantins-Araguaia Basin (Northern Brazil), Caused by Paracoccidioides sp | en_US |
Tipo del documento | Article | en_US |
DOI | 10.3390/jof8050502 | |
Resumen en Inglés | Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Brazil. The disease is caused by dimorphic fungi nested within the Paracoccidioides genus. We described 106 PCM cases (47.1 cases/year) at the Tropical Diseases Public Hospital of Tocantins State. PCM was prevalent in males and rural workers over 50 years; the chronic pulmonary form predominated in 67% of cases. The male-to-female ratio was 2.65:1, with more women affected than other endemic regions of Brazil. Urban or indoor activities were reported in women and are ascribed to disease urbanization. qPCR-based assays confirmed the identification of Paracoccidioides DNA in 37 biological specimens. Paracoccidioides sp. DNA was found in 53% of the environmental samples, suggesting autochthonous infections. Therefore, the Tocantins-Araguaia basin must be considered a novel hyperendemic area of PCM in Brazil, reinforcing the importance of including PCM as a notifiable disease, requiring specific diagnosis and health measures. | en_US |
Afiliación | Tocantins Department of Public Health. Palmas, TO, Brazil / University of São Paulo. Institute of Tropical Medicine. São Paulo, SP, Brazil. | en_US |
Afiliación | São Paulo State University Júlio de Mesquita Filho. Department of Chemical and Biological Sciences. Botucatu, SP, Brazil. | en_US |
Afiliación | Tocantins Department of Public Health. Palmas, TO, Brazil. | en_US |
Afiliación | University of Brasília. Faculty of Medicine. Núcleo de Medicina Tropical. Brasília, DF, Brazil. | en_US |
Afiliación | São Paulo State University Júlio de Mesquita Filho. Department of Chemical and Biological Sciences. Botucatu, SP, Brazil. | en_US |
Afiliación | Fundação Oswaldo Cruz. Fiocruz Brasília. Brasília, DF, Brasil. | en_US |
Afiliación | Federal University of Tocantins. Medical School. Araguaína, TO, Brazil. | en_US |
Afiliación | Catholic University of Brasília. Graduate Program in Genomic Sciences and Biotechnology. Brasília, DF, Brazil. | en_US |
Afiliación | São Paulo State University Júlio de Mesquita Filho. Department of Chemical and Biological Sciences. Botucatu, SP, Brazil. | en_US |
Afiliación | University of São Paulo. Institute of Tropical Medicine. São Paulo, SP, Brazil. | en_US |
Afiliación | University of Brasília. Faculty of Medicine. Núcleo de Medicina Tropical. Brasília, DF, Brazil. | en_US |
Palavras clave en Inglês | Tocantins-Araguaia basin | en_US |
Palavras clave en Inglês | Paracoccidioides brasiliensis | en_US |
Palavras clave en Inglês | Paracoccidioides lutzii | en_US |
Palavras clave en Inglês | Paracoccidioidomycosis | en_US |
Palavras clave en Inglês | Northern Brazil | en_US |
DeCS | Paracoccidioidomicose | en_US |
DeCS | Micose Fungoide | en_US |
DeCS | Fatores Epidemiológicos | en_US |
DeCS | Brasil | en_US |