Author | Menezes, Vinicius M. | |
Author | Nery, José Augusto C. | |
Author | Sales, Anna M. | |
Author | Miranda, Alice | |
Author | Galhardo, Maria Clara G. | |
Author | Bastos, Francisco Inácio Pinkusfeld Monteiro | |
Author | Sarno, Euzenir N. | |
Author | Hacker, Mariana A. | |
Access date | 2014-12-10T11:49:59Z | pt_BR |
Access date | 2015-01-05T15:49:40Z | |
Available date | 2015-01-05T15:49:40Z | |
Document date | 2014 | |
Citation | MENEZES, V. M. et al. Epidemiological and clinical patterns of 92 patients co-infected with hiv and mycobacterium leprae from Rio de Janeiro State, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, v.108, n.2, p. 63-70,2014. | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/9297 | |
Language | eng | en_US |
Rights | open access | en_US |
Title | Epidemiological and clinical patterns of 92 patients co-infected with HIV and Mycobacterium leprae from Rio de Janeiro State, Brazil | en_US |
Type | Article | en_US |
DOI | DOI:10.1093/trstmh/trt113 | |
Abstract | Background: Many articles have shown that HIV infection can modify the clinical course of leprosy, but very scant epidemiological and clinical data about this co-infection are available in the peer-reviewed literature.
Methods: We herein describe the geographical distribution and demographic characteristics of 92 HIV/Mycobacterium leprae co-infected patients assisted in a Brazilian Leprosy referral center. A multivariate analysis
was performed in order to establish clinical factors associated with type 1 reaction.
Results: Co-infected patient admissions have steadily increased over the last years at this referral center. Most patients were men, with a mean age of 32.3 years and presenting with the paucibacillary form of leprosy. The use
of antiretroviral therapy (ART) was the only factor associated with type 1 reaction. Most patients were living in the metropolitan area and the north sub area of Rio de Janeiro City.
Conclusion: Co-infected patients receiving ART have a greater chance to develop type 1 reaction. Patients living with both HIV and leprosy are likely to live in regions characterized by a high density impoverished population. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Rio de Janeiro, RJ, Brasil / CAPES Visiting researcher. Imperial College. London, UK. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil. | en_US |
Subject | Brazil | en_US |
Subject | Leprosy and HIV co-infection | en_US |
Subject | Social geography of leprosy | en_US |
Subject | Type 1 reaction | en_US |