Browsing by Author Batista, Denise da Gama Jaen

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Issue DateTitleAuthor(s)CopyrightType
2013Activities of Psilostachyin A an Cynaropicrin against Trypanosoma cruzi In Vitro and In VivoSilva, Cristiane França da; Batista, Denise da Gama Jaen; Araújo, Julianna Siciliano de; Batista, Marcos Meuser; Lionel, Jessica; Souza, Ellen Mello de; Hammer, Erica Ripoll; Silva, Patricia Bernardino da; Miert, Marta de; Adams, Michael; Zimmermann, Stefanie; Hamburger, Matthias; Brun, Reto; Schühly, Wolfang; Soeiro, Maria de Nazaré Correiaopen accessArticle
2016Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruziHoekstra, William J.; Hargrove, Tatiana Y.; Wawrzak, Zdzislaw; Batista, Denise da Gama Jaen; Silva, Cristiane F. da; Nefertiti, Aline S. G.; Rachakonda, Girish; Schotzinger, Robert J.; Villalta, Fernando; Soeiro, Maria de Nazaré C.; Lepesheva, Galina I.open accessArticle
2012CYP51 structures and structure-based development of novel, pathogen-specific inhibitory scaffoldsHargrove, Tatiana Y.; Kim, Kwangho; Soeiro, Maria de Nazaré Correia; Silva, Cristiane França da; Batista, Denise da Gama Jaen; Batista, Marcos Meuser; Yazlovitskaya, Eugenia M.; Waterman, Michael R.; Sulikowski, Gary A.; Lepesheva, Galina I.open accessArticle
2012Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas’ Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology StudiesZhu, Xiaohua; Liu, Qiang; Yang, Sihyung; Parman, Toufan; Green, Carol E.; Mirsalis, Jon C.; Soeiro, Maria de Nazaré Correia; Souza, Elen Mello de; Silva, Cristiane França da; Batista, Denise da Gama Jaen; Stephens, Chad E.; Banerjee, Moloy; Farahat, Abdelbasset A.; Munde, Manoj; Wilson, W. David; Boykin, David W.; Wang, Michael Zhuo; Werbovetz, Karl A.open accessArticle
2018Identification of Pyrazolo[3,4-e][1,4]thiazepin based CYP51 inhibitors as potential Chagas disease therapeutic alternative: In vitro and in vivo evaluation, binding mode prediction and SAR explorationFiuza, Ludmila Ferreira de Almeida; Peres, Raiza Brandão; Silva, Marianne Rocha Simões; Silva, Patricia Bernardino da; Batista, Denise da Gama Jaen; Silva, Cristiane França da; Gama, Aline Nefertiti Silva da; Reddy, Tummala Rama Krishna; Soeiro, Maria de Nazaré C.restricted accessArticle
2014In vitro and in vivo activity of the chloroaryl-substituted imidazole viniconazole against Trypanosoma cruziSilva, Cristiane França da; Batista, Denise da Gama Jaen; Batista, Marcos Meuser; Lionel, Jessica; Hammer, Erica Ripoll; Brun, Reto; Soeiro, Maria de Nazaré Correiaopen accessArticle
2012In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infectionSilva, Cristiane França da; Batista, Denise da Gama Jaen; Oliveira, Gabriel Melo; Souza, Elen Mello de; Hammer, Erica Ripoll; Silva, Patricia Bernardino da; Daliry, Anissa; Araujo, Julianna Siciliano; Britto, Constança; Rodrigues, Ana Carolina Mondaine; Liu, Zongying; Farahat, Abdelbasset A.; Kumar, Arvind; Boykin, David W.; Soeiro, Maria de Nazaré Correiaopen accessArticle
2013In Vitro and In Vivo Studies of the Antiparasitic Activity of Sterol 14 -Demethylase (CYP51) Inhibitor VNI against Drug-Resistant Strains of Trypanosoma cruziSoeiro, Maria Nazaré Correia; Souza, Elen Mello de; Silva, Cristiane França da; Batista, Denise da Gama Jaen; Batista, Marcos Meuser; Pavão, Beatriz Philot; Araújo, Julianna Siciliano; Aiub, Claudia Alessandra Fortes; Silva, Patrícia Bernardino da; Lionel, Jessica; Britto, Constança; Kim, Kwangho Kim; Sulikowski, Gary; Hargrove, Tatiana Y.; Waterman, Michael R.; Lepesheva, Galina I.open accessArticle
2008In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruziSilva, Cristiane França da; Batista, Marcos Meuser; Batista, Denise da Gama Jaen; Souza, Elen Mello de; Silva, Patrícia Bernardino da; Oliveira, Gabriel Melo de; Meuser, Andrea Souza; Shareef, Abdur-Rafay; Boykin, David W.; Soeiro, Maria de Nazaré C.restricted accessArticle
2016Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi ActivityMartins, Darliane A.; Gouvea, Ligiane R.; Muniz, Gabriel S. Vignoli; Louro, Sonia R.W.; Batista, Denise da Gama Jaen; Soeiro, Maria de Nazaré C.; Teixeira, Letícia R.open accessArticle