Browsing by Author "Batista, Alzir Azevedo"
Now showing items 1-20 of 21
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Antimalarial agents derived from metal-amodiaquine complexes with activity in multiple stages of the plasmodium life cycle
Colina-Vegas, Legna et al. | Date Issued: 2023 -
Antiparasitic activities of novel ruthenium/lapachol complexes.
Barbosa, Marília Imaculada Frazão et al. | Date Issued: 2014 -
Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents
Macedo, Taís Soares et al. | Date Issued: 2016 -
Complexos Paládio-Tioureias como fonte para obtenção de potentes e seletivos agentes Anti-T.Cruzi
Silva, Dahara Keyse Carvalho et al. | Date Issued: 2016A doença de Chagas é causada pelo protozoário T. cruzi e o seu tratamento atual se restringe ao benzonidazol. Apesar de possuir boas taxas de cura na fase aguda, o benzonidazol é ineficaz na fase crônica da doença. Diante ... -
Demonstração eficácia do derivado Mefloquina WV-41 em camundongos infectados com o Plasmodium Berghei
Araújo, Bruno Santos et al. | Date Issued: 2018A malária é uma das doenças infecciosas de maior incidência e que mais leva a óbito no mundo. Os fármacos disponíveis são capazes de combater o parasita no ciclo intraeritrocítico, no entanto há cepas resistentes ao ... -
Evaluation of anti-Trypanosoma cruzi activities of nitrosyl/nitro ruthenium complexes in vitro and in vivo
Bastos, Tanira Matutino et al. | Date Issued: 2012 -
Evaluation of anti-Trypanosoma cruzi activities of nitrosyl/nitro ruthenium complexes in vitro and in vivo.
Bastos, Tanira Matutino et al. | Date Issued: 2012 -
Nitro/nitrosyl ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death
Bastos, Tanira Matutino et al. | Date Issued: 2014 -
Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells
Costa, Cinara Oliveira D'Sousa et al. | Date Issued: 2017 -
Palladium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones: spectral characterization, structural studies and cytotoxic activity.
Rebolledo, Anayive Pérez et al. | Date Issued: 2005 -
Platinum(ii)-chloroquine complexes are antimalarial agents against blood and liver stages by impairing mitochondrial function
Macedo, Taís Soares et al. | Date Issued: 2017 -
Potência e eficácia de derivados da amodiaquina na Malária experimental
Silva, Mariana da Cruz Borges et al. | Date Issued: 2018A amodiaquina (AQ) é um fármaco antimalárico utilizado no tratamento da malária não complicada, sendo, de fato, mais eficaz, palatável e de menor custo do que a cloroquina (CQ), porém, devido aos relatos de eventos adversos ... -
Ru (II)–thyminate complexes new metallodrug candidates against tumor cells
Correa, Rodrigo de Souza et al. | Date Issued: 2018 -
Ru(II)-Thymine Complex Causes Cell Growth Inhibition and Induction of Caspase-Mediated Apoptosis in Human Promyelocytic Leukemia HL-60 Cells
Oliveira, Maiara de Souza et al. | Date Issued: 2018 -
Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling
Silva, Suellen Leila Rocha et al. | Date Issued: 2019 -
Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells
Neves, Sara Parente et al. | Date Issued: 2019 -
Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model.
Silva, Suellen Leila Rocha et al. | Date Issued: 2019 -
Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole
Corrêa, Rodrigo S. et al. | Date Issued: 2016 -
A ruthenium-based 5-fluorouracil complex with enhanced cytotoxicity and apoptosis induction action in HCT116 cells
Silva, Valdenizia Rodrigues et al. | Date Issued: 2018