Browsing by Author "Pires, Douglas Eduardo Valente"
Now showing items 1-20 of 37
-
Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design
Albanaz, Amanda Tábita da Silva et al. | Date Issued: 2017 -
A Computational Approach From Gene to Structure Analysis of the Human ABCA4 Transporter Involved in Genetic Retinal Diseases.
Trezza, Alfonso et al. | Date Issued: 2017 -
CSM-lig: a web server for assessing and comparing protein–small molecule affinities.
Pires, Douglas Eduardo Valente et al. | Date Issued: 2016 -
DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
Rodrigues, Carlos Henrique Miranda et al. | Date Issued: 2018 -
EasyVS: a user-friendly web-based tool for molecule library selection and structure-based virtual screening
Pires, Douglas Eduardo Valente et al. | Date Issued: 2020 -
Estudo computacional de desordem proteica nos genomas de Cryptococcus spp.
Tavares, Grace Santos | Date Issued: 2016Desde a década de 1990, a comunidade científica tem relatado um número crescente de proteínas e trechos que não apresentam uma conformação tridimensional estável e única, mas que são biologicamente ativas, o que contrasta ... -
Evaluating hierarchical machine learning approaches to classify biological databases.
Rezende, Pâmela Marinho et al. | Date Issued: 2022 -
Familial STAG2 germline mutation defines a new human cohesinopathy.
Soardi, Fernanda Caroline et al. | Date Issued: 2017 -
Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.
Coelho, Miguel B. et al. | Date Issued: 2016 -
GASS-WEB: a web server for identifying enzyme active sites based on genetic algorithms
Moraes, Joao P. A. et al. | Date Issued: 2017 -
Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype-phenotype correlations in the largest cohort of patients with AKU
Ascher, David B. et al. | Date Issued: 2019 -
Human LC3 and GABARAP subfamily members achieve functional specificity via specific structural modulations
Jatana, Nidhi et al. | Date Issued: 2019 -
Identification and in silico characterization of structural and functional impacts of genetic variants in milk protein genes in the Zebu breeds Guzerat and Gyr
Matosinho, Carolina Guimarães Ramos et al. | Date Issued: 2021 -
Identification and in silico characterization of structural and functional impacts of genetic variants in milk protein genes in the Zebu breeds Guzerat and Gyr.
Matosinho, Carolina Guimarães Ramos et al. | Date Issued: 2021 -
Identifying the molecular drivers of ALS-implicated missense mutations
Portelli, Stephanie et al. | Date Issued: 2022 -
In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity
Pires, Douglas Eduardo Valente et al. | Date Issued: 2016 -
Integração de dados de expressão gênica e proteômica em redes de interação proteína-proteína de Trypanosoma cruzi
Guimarães, Frederico Gonçalves | Date Issued: 2017Paradoxalmente vivemos um momento da pesquisa científica em que possuímos um volume abundante de dados, mas com dificuldades cada vez maiores de se obter informações a partir deles. Diversidade de formatos, dificuldade ... -
Kinact: a computational approach for predicting activating missense mutations in protein kinases
Rodrigues, Carlos Henrique Miranda et al. | Date Issued: 2018 -
mCSM-AB: a web server for predicting antibody-antigen affinity changes upon mutation with graph-based signatures
Pires, Douglas Eduardo Valente et al. | Date Issued: 2016 -
mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance.
Pires, Douglas Eduardo Valente et al. | Date Issued: 2016