| Author | Fernandes, Ligia Gabrielli | pt_BR |
| Author | Almeida, Maria da Conceição Chagas de | pt_BR |
| Author | Aquino, Estela Maria Motta Lima Leão de | pt_BR |
| Access date | 2015-07-07T18:55:01Z | |
| Available date | 2015-07-07T18:55:01Z | |
| Document date | 2015 | |
| Citation | FERNANDES, Ligia Gabrielli; ALMEIDA, Maria da Conceição Chagas de; AQUINO, Estela Maria Motta Lima Leão de. Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Maturitas, v. 81, n. 3, p. 398-405, 2015. | pt_BR |
| ISSN | 1873-4111 | |
| URI | https://www.arca.fiocruz.br/handle/icict/11115 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | pt_BR |
| Title | Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). | en |
| Type | Article | pt_BR |
| DOI | 10.1016/j.maturitas.2015.04.013 | |
| Abstract | Objectives: To propose plausible criteria with which to identify menopausal women with PCOS. Study design: A cross-sectional study involving the baseline data of 713 menopausal women at admission to the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) in Salvador, Bahia, Brazil. Main outcome measures: PCOS was identified by the presence oftwo ofthree criteria.(1)Ahistory of amenorrhea or oligomenorrhea (OL) (regular intermenstrual intervals ≥35 days during reproductive life); (2) clinical or biochemical hyperandrogenism (HA), identified by a score ≥5 points in a hirsutism questionnaire constructed and validated for women in this age group, or total or free testosterone ≥the 95th percentile for women considered normal; (3) insulin resistance (IR) (a homeostatic model assessment [HOMA] index ≥ 2.2). Validation was performed using probable epidemiological endpoints. Results: According to these criteria, 7.6% of the women in the sample had PCOS. Of these, 7.4% had HA and OL, 72.2%hadHAand IR, 14.8%had OL and IRand 5.6%,hadHA, OL and IR.Women withPCOS were younger, had had fewer pregnancies and entered menopause earlier. Positive associations were found between PCOS and overweight (PR: 1.31; 95%CI: 1.18–1.46), obesity (1.44; 1.01–2.06), carbohydrate metabolism disorders (impaired glucose tolerance and diabetes mellitus) (1.30; 1.03–1.65), and with diabetes alone (1.41; 0.83–2.39), although this latter association failed to reach statistical significance. Conclusion: The women selected in accordance with these criteria had the characteristics of PCOS that are not only expected, but also widely associated with this disorder. | en |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Bahia State Center for Diabetes and Endocrinology. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Subject | Polycistic ovary syndrome | en |
| Subject | Menopause | en |
| Subject | Insulin resistance | en |
