Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/11471
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dc.contributor.authorFogel, Jessica M.
dc.contributor.authorWang, Lei
dc.contributor.authorParsons, Teresa L.
dc.contributor.authorOu, San-San
dc.contributor.authorPiwowar-Manning, Estelle
dc.contributor.authorChen, Ying
dc.contributor.authorMudhune, Victor O.
dc.contributor.authorHosseinipour, Mina C.
dc.contributor.authorKumwenda, Johnstone
dc.contributor.authorHakim, James G.
dc.contributor.authorChariyalertsak, Suwat
dc.contributor.authorPanchia, Ravindre
dc.contributor.authorSanne, Ian
dc.contributor.authorKumarasamy, Nagalingeswaran
dc.contributor.authorGrinsztejn, Beatriz
dc.contributor.authorMakhema, Joseph
dc.contributor.authorPilotto, José
dc.contributor.authorSantos, Breno R.
dc.contributor.authorMayer, Kenneth H.
dc.contributor.authorMcCauley, Marybeth
dc.contributor.authorGamble, Theresa
dc.contributor.authorBumpus, Namandjé N.
dc.contributor.authorHendrix, Craig W.
dc.contributor.authorCohen, Myron S.
dc.contributor.authorEshleman, Susan H.
dc.date.accessioned2015-08-19T13:49:16Z
dc.date.available2015-08-19T13:49:16Z
dc.date.issued2013
dc.identifier.citationFOGEL, Jessica M.; et al. Undisclosed Antiretroviral Drug Use in a Multinational Clinical Trial (HIV Prevention Trials Network 052). J Infect Dis., v.208, n.10, p.1624-1628, 2013.
dc.identifier.issn1537-6613
dc.identifier.issn0022-1899
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/11471
dc.language.isoeng
dc.publisherOxford University Press
dc.rightsrestricted access
dc.titleUndisclosed Antiretroviral Drug Use in a Multinational Clinical Trial (HIV Prevention Trials Network 052)
dc.typeArticle
dc.identifier.doi10.1093/infdis/jit390
dc.description.abstractenThe HIV Prevention Trials Network 052 study enrolled serodiscordant couples. Index participants infected with human immunodeficiency virus reported no prior antiretroviral (ARV) treatment at enrollment. ARV drug testing was performed retrospectively using enrollment samples from a subset of index participants. ARV drugs were detected in 45 of 96 participants (46.9%) with an undetectable viral load, 2 of 48 (4.2%) with a low viral load, and 1 of 65 (1.5%) with a high viral load (P < .0001); they were also detected in follow-up samples from participants who were not receiving study-administered treatment. ARV drug testing may be useful in addition to self-report of ARV drug use in some clinical trial settings.
dc.creator.affilliationJohns Hopkins University. School of Medicine. Department of Pathology. Baltimore, Maryland, USA.
dc.creator.affilliationFred Hutchinson Cancer Research Center. Vaccine and Infectious Disease Division. Seattle, Washington, USA.
dc.creator.affilliationJohns Hopkins University. School of Medicine. Department of Medicine. Baltimore, Maryland, USA.
dc.creator.affilliationFred Hutchinson Cancer Research Center. Vaccine and Infectious Disease Division. Seattle, Washington, USA.
dc.creator.affilliationJohns Hopkins University. School of Medicine. Department of Pathology. Baltimore, Maryland, USA.
dc.creator.affilliationFred Hutchinson Cancer Research Center. Vaccine and Infectious Disease Division. Seattle, Washington, USA.
dc.creator.affilliationKEMRI-CDC HIV Research Branch. Kisumu, Kenya.
dc.creator.affilliationUNC Project. Kamuzu Central Hospital. Lilongwe. Malawi.
dc.creator.affilliationCollege of Medicine. Blantyre, Malawi.
dc.creator.affilliationUniversity of Zimbabwe. Department of Medicine. Harare. Zimbabwe.
dc.creator.affilliationChiang Mai University. Research Institute for Health Sciences. Thailand.
dc.creator.affilliationUniversity of the Witwatersrand. Faculty of Health Sciences. Department of Medicine. Perinatal HIV Research Unit. Johannesburg, South Africa.
dc.creator.affilliationUniversity of the Witwatersrand. Faculty of Health Sciences. Department of Medicine. Clinical HIV Research Unit. Johannesburg, South Africa.
dc.creator.affilliationY. R. Gaitonade Center for AIDS Research and Education, Chennai, India.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratorio de Pesquisa Clinica em DST/AIDS . Rio de Janeiro, RJ, Brasil.
dc.creator.affilliation19Botswana– Harvard School of Public Health AIDS Initiative Partnership, Gaborone.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil / Hospital Geral de Nova Iguaçu. Nova Iguaçu, RJ, Brasil.
dc.creator.affilliationHospital Nossa Senhora da Conceicao. Porto Alegre, RS, Brasil.
dc.creator.affilliationFenway Health. Boston, Massachusetts, USA.
dc.creator.affilliationFHI360. Washington, District of Columbia, USA.
dc.creator.affilliationFHI360. Durham, North Carolin, USA.
dc.creator.affilliationJohns Hopkins University. School of Medicine. Department of Medicine. Baltimore, Maryland, USA.
dc.creator.affilliationJohns Hopkins University. School of Medicine. Department of Medicine. Baltimore, Maryland, USA.
dc.creator.affilliationUniversity of North Carolina. Department of Medicine. Chapel Hill, NC, USA.
dc.creator.affilliationJohns Hopkins University. School of Medicine. Department of Pathology. Baltimore, Maryland, USA.
dc.subject.enHIV
dc.subject.enAntiretroviral drug
dc.subject.enSelf-report
dc.subject.enHPTN 052
dc.subject.enAfrica
dc.subject.enClinical trial
dc.subject.decsHIV
dc.subject.decsEnsaio clínico
dc.subject.decsTerapia Antirretroviral de Alta Atividade
dc.subject.decsÁfrica
Appears in Collections:INI - Artigos de Periódicos
IOC - Artigos de Periódicos

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