Author | Xavier, Maria da Penha Trindade Pinheiro | |
Author | Costa, Filipe Anibal Carvalho | |
Author | Rocha, Mônica Simões | |
Author | Andrade, Juliana da Silva Ribeiro de | |
Author | Diniz, Fernanda Kreischer Bandeira | |
Author | Andrade, Thais Ramos de | |
Author | Miagostovich, Marize Pereira | |
Author | Leite, José Paulo Gagliardi | |
Author | Volotão, Eduardo de Mello | |
Access date | 2016-05-17T12:51:43Z | |
Available date | 2016-05-17T12:51:43Z | |
Document date | 2015 | |
Citation | XAVIER, Maria da Penha Trindade Pinheiro; et al. Surveillance of Human Astrovirus Infection in Brazil: The First Report of MLB1 Astrovirus. Plos One, v.10, n.8, e0135687, 12p, Aug. 2015. | pt_BR |
ISSN | 1932-6203 | |
URI | https://www.arca.fiocruz.br/handle/icict/14307 | |
Language | eng | pt_BR |
Publisher | Public Library of Science | pt_BR |
Rights | open access | pt_BR |
Title | Surveillance of Human Astrovirus Infection in Brazil: The First Report of MLB1 Astrovirus | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal. pone.0135687 | |
Abstract | Human astrovirus (HAstV) represents the third most common virus associated with acute
diarrhea (AD). This study aimed to estimate the prevalence of HAstV infection in Brazilian
children under 5 years of age with AD, investigate the presence of recently described
HAstV strains, through extensive laboratory-based surveillance of enteric viral agents in
three Brazilian coastal regions between 2005 and 2011. Using reverse transcription-polymerase
chain reaction (RT-PCR), the overall HAstV detection rate reached 7.1% (207/
2.913) with percentage varying according to the geographic region: 3.9% (36/921) in the
northeast, 7.9% in the south (71/903) and 9.2% in the southeast (100/1.089) (p < 0.001).
HAstV were detected in cases of all age groups. Detection rates were slightly higher during
the spring. Nucleotide sequence analysis of a 320-bp ORF2 fragment revealed that HAstV-
1 was the predominant genotype throughout the seven years of the study. The novel AstVMLB1
was detected in two children with AD from a subset of 200 samples tested, demonstrating
the circulation of this virus both the in northeastern and southeastern regions of
Brazil. These results provide additional epidemiological and molecular data on HAstV circulation
in three Brazilian coastal regions, highlighting its potential to cause infantile AD. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Human astrovirus (HAstV) | pt_BR |
Subject | Infection | pt_BR |
Subject | Surveillance | pt_BR |
Subject | Brazil | pt_BR |
Subject | Diarrhea | pt_BR |
DeCS | Mamastrovirus | pt_BR |
DeCS | Infecção | pt_BR |
DeCS | Vigilância | pt_BR |
DeCS | Brasil | pt_BR |
DeCS | Diarréia | pt_BR |