Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/17645
Title: Wild, synanthropic and domestic hosts of Leishmania in an endemic area of cutaneous leishmaniasis in Minas Gerais State, Brazil
Authors: Quaresma, Patrícia Flávia
Rêgo, Felipe Dutra
Botelho, Helbert Antonio
Silva, Shara Regina da
Moura Júnior, Airton Jose
Teixeira Neto, Rafael Gonçalves
Madeira, Filipe M.
Carvalho, Maria Beatriz
Paglia, Adriano Pereira
Melo, Maria Norma
Gontijo, Célia Maria Ferreira
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Exatas e Biológicas. Departamento de Biologia Geral. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Exatas e Biológicas. Departamento de Biologia Geral. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Exatas e Biológicas. Departamento de Biologia Geral. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Exatas e Biológicas. Departamento de Biologia Geral. Belo Horizonte, MG, Brazil
Universidade Federal de Minas Gerais. Instituto de Ciências Exatas e Biológicas. Departamento de Parasitologia. Belo Horizonte, MG, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Leishmanioses. Belo Horizonte, MG, Brazil
Abstract: Domestic, synanthropic and wild hosts of Leishmania spp. parasites were studied in an area endemic for American tegumentary leishmaniasis (ATL), specifically in northern Minas Gerais State, Brazil. Domestic dogs and small forest mammals are reservoir hosts for L. (Leishmania) infantum. However, the role that these animals play in the transmission cycle of the Leishmania spp. that cause cutaneous leishmaniasis is not well known. This study evaluated 72 rodents, 25 marsupials and 98 domestic dogs found in two villages of the Xakriabá Indigenous Territory, an area of intense ATL transmission. A total of 23 dogs (23.47%) were shown to be positive according to at least one test; 8 dogs (8.16%) tested positive in a single serological test and 15 dogs (15.31%) tested positive by IFAT and ELISA. Eleven dogs were euthanised to allow for molecular diagnosis, of which nine (81.8%) tested positive by PCR for Leishmania in at least one tissue. Seven animals were infected only with L. (L.) infantum, whilst two displayed a mixed infection of L. (L.) infantum and L. (V.) braziliensis. Isoenzymatic characterisation identified L. (L.) infantum parasites isolated from the bone marrow of two dogs. Of the 97 small mammals captured, 24 tested positive for Leishmania by PCR. The results showed that L. (V.) braziliensis, L. (L.) infantum and L. (V.) guyanensis are circulating among wild and synanthropic mammals present in the Xakriabá Reserve, highlighting the epidemiological diversity of ATL in this region.
Keywords: Leishmania
Host reservoirs
Dogs
Mixed infection
PCR
Brazil
keywords: Leishmaniose
hospedeiro
Issue Date: 2011
Publisher: Oxford University Press
Citation: QUARESMA Patrícia Flávia et al. Wild, synanthropic and domestic hosts of Leishmania in an endemic area of cutaneous leishmaniasis in Minas Gerais State, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 105, n. 10, p. 579-585, 2011.
DOI: 10.1016/j.trstmh.2011.07.005
ISSN: 0035-9203
Copyright: restricted access
Appears in Collections:MG - IRR - Artigos de Periódicos

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