Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/17983
Full metadata record
DC FieldValue
dc.contributor.authorAires, Caio Augusto Martins
dc.contributor.authorPereira, Polyana Silva
dc.contributor.authorAsensi, Marise Dutra
dc.contributor.authorAssef, Ana Paula D'Alincourt Carvalho
dc.date.accessioned2017-03-09T13:30:09Z
dc.date.available2017-03-09T13:30:09Z
dc.date.issued2016
dc.identifier.citationAIRES, Caio Augusto Martins; et al. MgrB mutations mediating polymyxin B resistance in Klebsiella pneumoniae isolates from rectal surveillance swabs in Brazil. Antimicrobial Agents and Chemotherapy, v.61, n.3, 15p, Sept. 2016.
dc.identifier.issn0066-4804
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/17983
dc.language.isoeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subject.otherKlebsiella pneumoniae
dc.subject.otherPolimixina B
dc.subject.otherTipagem Molecular
dc.subject.otherResistência a medicamentos
dc.titlemgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil
dc.typeArticle
dc.identifier.doi10.1128/AAC.01456-16
dc.description.abstractenWe aimed to investigate polymyxin B (PMB) resistance and its molecular mechanisms in 126 Klebsiella pneumoniae isolates from rectal swabs in Brazil. Ten isolates exhibited PMB resistance with interruption of mgrB gene by insertion sequences or missense mutations. Most of the PMB-resistant isolates harbored blaKPC-2 (n = 8) and belonged to clonal complex 258 (CC258) (n = 7). These results highlight the importance of monitoring the spread of polymyxin-resistant bacteria in hospitals, since few options remain to treat multidrug-resistant isolates.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ. Brasil.
dc.subject.enPolymyxin B resistance
dc.subject.enKlebsiella pneumoniae
dc.subject.enMolecular typing
dc.subject.enMrgB mutation
dc.identifier.eissn1098-6596
Appears in Collections:IOC - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
ve_caio_ayres_etal_IOC_2016.pdf.Versão do Editor361.36 kBUnknownView/Open
caio_ayres_etal_IOC_2016.pdfAccepted Manuscript853.95 kBAdobe PDFView/Open



FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.