Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/18804
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dc.contributor.authorAlbuquerque, Maria de Fátima Pessoa Militão de
dc.contributor.authorSouza, Wayner V. de
dc.contributor.authorMendes, Antônio da Cruz G.
dc.contributor.authorLyra, Tereza M.
dc.contributor.authorXimenes, Ricardo A.
dc.contributor.authorAraújo, Thália V.
dc.contributor.authorBraga, Cynthia
dc.contributor.authorMiranda-Filho, Demócrito B.
dc.contributor.authorMartelli, Celina M.
dc.contributor.authorRodrigues, Laura C.
dc.date.accessioned2017-05-09T19:18:29Z
dc.date.available2017-05-09T19:18:29Z
dc.date.issued2016
dc.identifier.citationALBUQUERQUE, Maria de Fátima Pessoa Militão de et al. Pyriproxyfen and the microcephaly epidemic in Brazil - an ecological approach to explore the hypothesis of their association. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 111, n. 12, p. 774–776, 31 out. 2016.
dc.identifier.issn1678-8060
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/18804
dc.language.isoen
dc.rightsopen access
dc.titlePyriproxyfen and the microcephaly epidemic in Brazil: an ecological approach to explore the hypothesis of their association
dc.typeArticle
dc.identifier.doi10.1590/0074-02760160291
dc.description.abstractenThe microcephaly epidemic in Brazil generated intense debate regarding its causality, and one hypothesised cause of this epidemic, now recognised as congenital Zika virus syndrome, was the treatment of drinking water tanks with pyriproxyfen to control Aedes aegypti larvae. We present the results of a geographical analysis of the association between the prevalence of microcephaly confirmed by Fenton growth charts and the type of larvicide used in the municipalities that were home to the mothers of the affected newborns in the metropolitan region of Recife in Pernambuco, the state in Brazil where the epidemic was first detected. The overall prevalence of microcephaly was 82 per 10,000 live births in the three municipalities that used the larvicide Bti (Bacillus thuringiensis israelensis) instead of pyriproxyfen, and 69 per 10,000 live births in the eleven municipalities that used pyriproxyfen. The difference was not statistically significant. Our results show that the prevalence of microcephaly was not higher in the areas in which pyriproxyfen was used. In this ecological approach, there was no evidence of a correlation between the use of pyriproxyfen in the municipalities and the microcephaly epidemic.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva. Recife, PE, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva. Recife, PE, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva. Recife, PE, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva. Recife, PE, Brasil.
dc.creator.affilliationUniversidade Federal de Pernambuco. Recife, PE, Brasil / Universidade de Pernambuco. Recife, PE, Brasil.
dc.creator.affilliationUniversidade de Pernambuco. Recife, PE, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva. Recife, PE, Brasil.
dc.creator.affilliationUniversidade de Pernambuco. Recife, PE, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Saúde Coletiva. Recife, PE, Brasil.
dc.creator.affilliationLondon School of Hygiene and Tropical Medicine. London, UK.
dc.subject.decsInsecticidas / efeitos adversos
dc.subject.decsMicrocefalia / quimicamente induzida
dc.subject.decsPiridinas / efeitos adversos
dc.subject.decsInfecção por vírus Zika / prevenção & controle
dc.subject.decsControle de Mosquito
Appears in Collections:PE - IAM - Artigos de Periódicos

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