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THE INFLUENCE OF THE STRAIN OF TRYPANOSOMA CRUZI IN PLACENTAL INFECTIONS IN MICE
Andrade, Sonia Gumes | Fecha del documento:
1982
Autor
Afiliación
Federal University of Bahia. Faculty of Medicine. Department of Pathology. Salvador, BA, Brazil
Resumen en ingles
Pregnant female mice were infected with Trypanosoma
cruzi strains which differed according to several
parameters and were classified as three different
types. Mice were killed during either the acute or the
chronic phase of infection. Animals’ tissues and
foetuses together with the placentas, were studied
histopathologically. Clear cut differences were noted
in the incidence of placental parasitism and in the
localization of amastigotes in the vascular sinus of the
placenta amongst the animals in the acute phase of the
infection with different strains. No parasitism of the
foetal tissues was seen. The incidence of placental
parasitism reached 98% for the Colombian strain,
18.4% for the Peruvian strain, 17% for the Y strain
and 13.2% for the Honmina strain (isolated from a
woman that transmitted the infection to twins). The
presence of parasites in the vascular part of the
placenta was prominent with the Colombian strain and
rare with the others. These experimental data seem to
show that parasite strain plays a role in congenital T.
cruzi infection.
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