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A FULLY ANNOTATED GENOME SEQUENCE OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE 1 (HTLV-1)
Autor(es)
Afiliação
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Bahian School of Medicine and Public Health. Salvador, BA, Brazil
Catholic University of Salvador. Salvador, BA, Brazil
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Bahian School of Medicine and Public Health. Salvador, BA, Brazil
Catholic University of Salvador. Salvador, BA, Brazil
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil
Resumo em Inglês
In the next generation of genome sequencing, sequence annotation
plays an important role with respect to genome evaluation. The aim
of annotation is to identify key features in the genome, such as genes
and their products. Although annotation tools are available and some
sequence features have been published, annotation information for
many complete and partial genomes of Human T-Cell Lymphotropic
Virus Type 1 (HTLV-1) remains unavailable from GenBank. Sequence
analysis is critical to the understanding of the pathogenesis of HTLV-1,
and a well-annotated reference sequence is an essential component in
this analysis. More accurate and complete information about the HTLV-1
genome can assist the scientific community in investigations on possible
therapeutic and prophylactic vaccines, as well as aid studies on the
pathogenesis of HTLV-1-associated diseases. Here we describe for the
first time the complete nucleotide position annotation of the frequently
used HTLV-1 reference sequence, ATK1 (accession number: J02029.1).
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