| Author | Rezende, Antonio M. | |
| Author | Assis, Ludmila A. | |
| Author | Nunes, Eduardo C. | |
| Author | Costa Lima, Tamara D. da | |
| Author | Marchini, Fabrício Klerynton | |
| Author | Freire, Eden R. | |
| Author | Reis, Christian R. S. | |
| Author | Melo Neto, Osvaldo P. de | |
| Access date | 2017-10-05T11:45:31Z | |
| Available date | 2017-10-05T11:45:31Z | |
| Document date | 2014 | |
| Citation | REZENDE, Antonio M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis. BMC Genomics, v. 15, n. 1175, p. 1-19, 2014. | pt_BR |
| ISSN | 1471-2164 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/22775 | |
| Language | por | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Trypanosoma | pt_BR |
| Title | The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1186/1471-2164-15-1175 | |
| Abstract | The initiation of translation in eukaryotes is supported by the action of several eukaryotic Initiation Factors (eIFs). The largest of these is eIF3, comprising of up to thirteen polypeptides (eIF3a through eIF3m), involved in multiple stages of the initiation process. eIF3 has been better characterized from model organisms, but is poorly known from more diverged groups, including unicellular lineages represented by known human pathogens. These include the trypanosomatids (Trypanosoma and Leishmania) and other protists belonging to the taxonomic supergroup Excavata (Trichomonas and Giardia sp.). | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Genômica Funcional. Curitiba, PR, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil. | pt_BR |
| Subject | Prokaryotic Initiation Factor-3 | pt_BR |
| Subject | Protein Biosynthesis | pt_BR |
| Subject | Protozoan Infections | pt_BR |
| Subject in Spanish | Factor 3 Procariótico de Iniciación | pt_BR |
| Subject in Spanish | Biosíntesis de Proteínas | pt_BR |
| Subject in Spanish | Infecciones por Protozoos | pt_BR |
| DeCS | Fator de Iniciação 3 em Procariotos | pt_BR |
| DeCS | Biossíntese de Proteínas | pt_BR |
| DeCS | Infecções por Protozoários | pt_BR |
