| Author | Rocha, Vinicius | |
| Author | Nonato, Fabiana Regina | |
| Author | Soares, Milena Botelho Pereira | |
| Access date | 2017-12-28T17:41:59Z | |
| Available date | 2017-12-28T17:41:59Z | |
| Document date | 2012 | |
| Citation | ROCHA, V.; NONATO, F. R.; SOARES, M. B. P. In vitro activity of antimalarial drugs against Leishmania amazonensis. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/23830 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Leishmania amazonensis | pt_BR |
| Subject in Portuguese | Drogas | pt_BR |
| Subject in Portuguese | Tratamento com medicamentos | pt_BR |
| Subject in Portuguese | Mefloquina | pt_BR |
| Subject in Portuguese | Leishmaniose cutanea | pt_BR |
| Title | In vitro activity of antimalarial drugs against Leishmania amazonensis | pt_BR |
| Type | Papers presented at events | pt_BR |
| Abstract | Introduction: Leishmaniasis comprises a broad spectrum of diseases caused by Leishmania parasites.
Treatment with the first-line drugs for leishmaniasis, the pentavalent antimonials, can be complicated by
side effects, less sensitivity or resistance of some Leishmania species, variations in pharmacokinetics,
drug-host immune response interaction and high cost. Therefore, it is pivotal the development of safer,
cheaper and more effective treatments for leishmaniasis. Drug repositioning is a strategy to identify and
develop new uses for existing drugs, reducing expenditures and research time. In this context, the aim of
this work was to evaluate the antileishmanial activity of antimalarial drugs. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Engenharia Tecidual e Imunofarmacologia. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Engenharia Tecidual e Imunofarmacologia. Salvador, BA, Brasil | pt_BR |
| Affilliation | Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil | pt_BR |
| Subject | Leishmania amazonensis | pt_BR |
| Subject | Drugs | pt_BR |
| Subject | Drug | pt_BR |
| Subject | Mefloquine | pt_BR |
| Subject | Cutaneous leishmaniasis | pt_BR |
| Subject | treatment | pt_BR |
