| Author | González, Mariela Natacha | |
| Author | Mello, Wallace de | |
| Author | Butler-Browne, Gillian S. | |
| Author | Barbosa, Suse Dayse Silva | |
| Author | Mouly, Vincent | |
| Author | Savino, Wilson | |
| Author | Riederer, Ingo | |
| Access date | 2018-02-15T14:58:23Z | |
| Available date | 2018-02-15T14:58:23Z | |
| Document date | 2017 | |
| Citation | GONZÁLEZ, Mariela Natacha; et al. HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway. Skeletal Muscle, v.7:20, 13p, 2017. | pt_BR |
| ISSN | 2044-5040 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/24836 | |
| Language | eng | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Laminina | pt_BR |
| Subject in Portuguese | Proteínas Proto-Oncogênicas c-met | pt_BR |
| Subject in Portuguese | Fibronectinas | pt_BR |
| Subject in Portuguese | Metaloproteinases da Matriz | pt_BR |
| Subject in Portuguese | Migração | pt_BR |
| Title | HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway | pt_BR |
| Type | Article | |
| DOI | 10.1186/s13395-017-0138-6 | |
| Abstract | The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle regeneration, along with extracellular matrix (ECM) molecules. In this study, we aimed at determining whether HGF is able to interact with ECM proteins, particularly laminin 111 and fibronectin, and to modulate human myoblast migration. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Sorbonne Universités., Université Pierre et Marie Curie. Center for Research in Myology. Boulevard de l’hôpital. Paris, France | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Câncer. Departamento de Pesquisa Clínica. Rio de Janeiro, RJ, Brasil | pt_BR |
| Affilliation | Sorbonne Universités., Université Pierre et Marie Curie. Center for Research in Myology. Boulevard de l’hôpital. Paris, France | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Ciência e Tecnologia em Neuroimunomodulação. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Myoblast transplantation | pt_BR |
| Subject | HGF | pt_BR |
| Subject | Migration | pt_BR |
| Subject | Laminin | pt_BR |
| Subject | Fibronectin | pt_BR |
| Subject | Matrix metalloproteinases | pt_BR |
| Subject | MAPK/ERK | pt_BR |
