Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/24913
Title: Neutralizing antibodies for orthobunyaviruses in Pantanal, Brazil
Authors: Corrêa, Alex Pauvolid
Campos, Zilca
Soares, Raquel
Nogueira, Rita Maria Ribeiro
Komar, Nicholas
Affilliation: Centers for Disease Control and Prevention. Arbovirus Diseases Branch. Fort Collins, CO, USA.
EMBRAPA Pantanal. Ministério da Agricultura Pecuária e Abastecimento. Corumbá, MS, Brasil.
EMBRAPA Pantanal. Ministério da Agricultura Pecuária e Abastecimento. Corumbá, MS, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ. Brasil.
Centers for Disease Control and Prevention. Arbovirus Diseases Branch. Fort Collins, CO, USA.
Abstract: The Pantanal is a hotspot for arbovirus studies in South America. Various medically important flaviviruses and alphaviruses have been reported in domestic and wild animals in the region. To expand the knowledge of local arbovirus circulation, a serosurvey for 14 Brazilian orthobunyaviruses was conducted with equines, sheep and free-ranging caimans. Sera were tested for specific viral antibodies using plaque-reduction neutralization test (PRNT). Monotypic reactions were detected for Maguari, Xingu, Apeu, Guaroa, Murutucu, Oriboca, Oropouche and Nepuyo viruses. Despite the low titers for most of the orthobunyaviruses tested, the detection of monotypic reactions for eight orthobunyaviruses suggests the Pantanal as a region of great orthobunyavirus diversity. The present data, in conjunction with previous studies that detected a high diversity of other arboviruses, ratify the Pantanal as an important natural reservoir for sylvatic and medically important arboviruses in Brazil.
Keywords: orthobunyaviruses
Pantanal
antibodies
Brazil
keywords: Anticorpos
Orthobunyavirus
Pantanal
Brasil
Issue Date: 2017
Publisher: Public Library of Science
Citation: CORRÊA, Alex Pauvolid; et al. Neutralizing antibodies for orthobunyaviruses in Pantanal, Brazil. PLoS Negl Trop Dis., v.11, n.11, e0006014, 11p, Nov. 2017.
DOI: 10.1371/journal.pntd.0006014
ISSN: 1935-2727
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
ritamaria2_nogueira_etal_IOC_2017.pdf849.17 kBAdobe PDFView/Open


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.