Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/24913
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dc.contributor.authorCorrêa, Alex Pauvolid
dc.contributor.authorCampos, Zilca
dc.contributor.authorSoares, Raquel
dc.contributor.authorNogueira, Rita Maria Ribeiro
dc.contributor.authorKomar, Nicholas
dc.date.accessioned2018-02-22T13:45:04Z
dc.date.available2018-02-22T13:45:04Z
dc.date.issued2017
dc.identifier.citationCORRÊA, Alex Pauvolid; et al. Neutralizing antibodies for orthobunyaviruses in Pantanal, Brazil. PLoS Negl Trop Dis., v.11, n.11, e0006014, 11p, Nov. 2017.
dc.identifier.issn1935-2727
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/24913
dc.language.isoeng
dc.publisherPublic Library of Science
dc.rightsopen access
dc.subject.otherAnticorpos
dc.subject.otherOrthobunyavirus
dc.subject.otherPantanal
dc.subject.otherBrasil
dc.titleNeutralizing antibodies for orthobunyaviruses in Pantanal, Brazil
dc.typeArticle
dc.identifier.doi10.1371/journal.pntd.0006014
dc.description.abstractenThe Pantanal is a hotspot for arbovirus studies in South America. Various medically important flaviviruses and alphaviruses have been reported in domestic and wild animals in the region. To expand the knowledge of local arbovirus circulation, a serosurvey for 14 Brazilian orthobunyaviruses was conducted with equines, sheep and free-ranging caimans. Sera were tested for specific viral antibodies using plaque-reduction neutralization test (PRNT). Monotypic reactions were detected for Maguari, Xingu, Apeu, Guaroa, Murutucu, Oriboca, Oropouche and Nepuyo viruses. Despite the low titers for most of the orthobunyaviruses tested, the detection of monotypic reactions for eight orthobunyaviruses suggests the Pantanal as a region of great orthobunyavirus diversity. The present data, in conjunction with previous studies that detected a high diversity of other arboviruses, ratify the Pantanal as an important natural reservoir for sylvatic and medically important arboviruses in Brazil.
dc.creator.affilliationCenters for Disease Control and Prevention. Arbovirus Diseases Branch. Fort Collins, CO, USA.
dc.creator.affilliationEMBRAPA Pantanal. Ministério da Agricultura Pecuária e Abastecimento. Corumbá, MS, Brasil.
dc.creator.affilliationEMBRAPA Pantanal. Ministério da Agricultura Pecuária e Abastecimento. Corumbá, MS, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ. Brasil.
dc.creator.affilliationCenters for Disease Control and Prevention. Arbovirus Diseases Branch. Fort Collins, CO, USA.
dc.subject.enorthobunyaviruses
dc.subject.enPantanal
dc.subject.enantibodies
dc.subject.enBrazil
dc.identifier.eissn1935-2735
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