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https://www.arca.fiocruz.br/handle/icict/24949
R&D IN VACCINES TARGETING NEGLECTED DISEASES: AN EXPLORATORY CASE STUDY CONSIDERING FUNDING FOR PREVENTIVE TUBERCULOSIS VACCINE DEVELOPMENT FROM 2007 TO 2014
Tuberculose
Vacinas contra a tuberculose
Pesquisa
Ensaios clínicos como assunto
Author
Affilliation
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil
Federal University of Bahia. Institute of Collective Health. Salvador, BA, Brazil
Federal University of Southern Bahia. Institute of Humanities Arts and Sciences. Itabuna, BA, Brazil
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil
Federal University of Bahia. Institute of Collective Health. Salvador, BA, Brazil
Federal University of Southern Bahia. Institute of Humanities Arts and Sciences. Itabuna, BA, Brazil
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil
Abstract
Based on an exploratory case study regarding the types of institutions funding the research and development to obtain new tuberculosis vaccines, this article intends to provoke discussion regarding the provision of new vaccines targeting neglected disease. Although our findings and discussion are mainly relevant to the case presented here, some aspects are more generally applicable, especially regarding the dynamics of development in vaccines to prevent neglected diseases. Taking into account the dynamics of innovation currently seen at work in the vaccine sector, a highly concentrated market dominated by few multinational pharmaceutical companies, we feel that global PDP models can play an important role throughout the vaccine development cycle. In addition, the authors call attention to issues surrounding the coordination of actors and resources in the research, development, manufacturing, and distribution processes of vaccine products arising from PDP involvement.
Keywords in Portuguese
Doenças negligenciadasTuberculose
Vacinas contra a tuberculose
Pesquisa
Ensaios clínicos como assunto
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