Author | Kauffmann, Carla | |
Author | Ethur, Eduardo Miranda | |
Author | Arossi, Kelen | |
Author | Hoehne, Lucélia | |
Author | Freitas, Elisete Maria de | |
Author | Machado, Gérzia Maria de Carvalho | |
Author | Cavalheiro, Marilene Marcuzzo do.Canto | |
Author | Flach, Adriana | |
Author | Costa, Luiz Antônio Mendonça Alves da | |
Author | Gnoatto, Simone Cristina Baggio | |
Access date | 2018-06-19T12:14:33Z | |
Available date | 2018-06-19T12:14:33Z | |
Document date | 2017 | |
Citation | KAUFFMANN, Carla; et al. Chemical composition andf evaluation preliminary of Antileishmanial activity in vitro of essential oil from leaves of Eugenia pitanga, a nati ve species of southern Brazil Journal of Essential Oil Bearing Plants, v.20, n.2, 11p, 2017. | pt_BR |
ISSN | 0972-060X | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/26939 | |
Language | eng | pt_BR |
Publisher | Taylor & Francis | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Atividade antileishmanial | pt_BR |
Subject in Portuguese | Composição química | pt_BR |
Subject in Portuguese | In vitro | pt_BR |
Subject in Portuguese | Óleo essencial | pt_BR |
Subject in Portuguese | Eugenia pitanga | pt_BR |
Subject in Portuguese | Sul do Brasil | pt_BR |
Title | Chemical Composition and Evaluation Preliminary of Antileishmanial Activity in vitro of Essential Oil from Leaves of Eugenia pitanga, A Native Species of Southern of Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1080/0972060X.2017.1281767 | |
Abstract | Eugenia pitanga (O.Berg) Nied., Myrtaceae, popularly known as pitanga-do-campo, is a species native from Pampa biome, in southern of Brazil and is popularly used as antidiarrheal, anti-rheumatic, stimulant and febrifuge. The aim of this work was to determine the chemical composition of essential oil from fresh leaves of Eugenia pitanga (O.Berg) Nied. Preliminaries data about antileishmanial activity in vitro of essential oil against promastigotes forms of Leishmania amazonensis are presented. The method to determine the chemical composition of the essential oil from fresh leaves of E. pitanga (EoEp) was gas chromatography-mass spectrometry. EoEp was assayed in vitro for antileishmanial activity against promastigotes of Leishmania amazonensis. The EoEp comprised 57 components and was rich in oxygenated sesquiterpenes (72.97 %) with spathulenol (15.34 %), globulol (10.93 %) and (2E,6E) methyl farnesoate (7.40 %) as the major constituents. EoEp was effective against L. amazonensis promastigotes with IC50 value of 6.10 ± 1.80 μg/mL. This work reports for the first time the composition of essential oil from leaves of E. pitanga from Pampa Biome, and it suggests the importance of continuing the studies in order to explain the antileishmanial activity. | pt_BR |
Affilliation | Centro Universitário UNIVATES. Centro de Ciências Biológicas e da Saúde. Lajeado, RS, Brasil. | pt_BR |
Affilliation | Centro Universitário UNIVATES. Centro de Ciências Exatas e Tecnológicas. Lajeado, RS, Brasil. | pt_BR |
Affilliation | Centro Universitário UNIVATES. Centro de Ciências Biológicas e da Saúde. Lajeado, RS, Brasil. | pt_BR |
Affilliation | Centro Universitário UNIVATES. Centro de Ciências Exatas e Tecnológicas. Lajeado, RS, Brasil. | pt_BR |
Affilliation | Centro Universitário UNIVATES. Centro de Ciências Biológicas e da Saúde. Lajeado, RS, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | Universidade Federal de Roraima. Departamento de Química. Boa Vista, RR, Brasil. | pt_BR |
Affilliation | Universidade Federal de Roraima. Departamento de Química. Boa Vista, RR, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio Grande do Sul. Faculdade de Farmácia. Laboratório de Fitoquímica e Síntese Orgânica. Porto Alegre, RS, Brasil. | pt_BR |
Subject | Antileishmanial activity | pt_BR |
Subject | Eugenia pitanga | pt_BR |
Subject | Chemical composition | pt_BR |
Subject | in vitro | pt_BR |
Subject | Essential oil | pt_BR |
Subject | Southern Brazil | pt_BR |
Subject | Leishmania amazonensis | pt_BR |
Subject | Myrtaceae | pt_BR |
e-ISSN | 0976-5026 | |
Embargo date | 2030-01-01 | |