Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/2746
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dc.contributor.authorCaldas, Arlene de Jesus Mendes
dc.contributor.authorCosta, Jackson Mauricio Lopes
dc.contributor.authorAquino, Dorlene Maria Cardoso de
dc.contributor.authorSilva, Antonio Augusto Moura da
dc.contributor.authorBarral Netto, Manoel
dc.contributor.authorBarral, Aldina Maria Prado
dc.date.accessioned2011-07-04T18:44:37Z
dc.date.available2011-07-04T18:44:37Z
dc.date.issued2006
dc.identifier.citationCALDAS, A. J. M. et al. Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis? Acta Tropica, v.97, n.3, p.252-258, 2006.
dc.identifier.issn0001-706X
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/2746
dc.language.isopor
dc.rightsopen access
dc.subject.otherLeishmaniose Visceral Americana
dc.subject.otherCrianças
dc.subject.otherAdultos
dc.subject.otherHipersensibilidade tardia
dc.subject.otherResposta Linfoproliferativa
dc.titleAre there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
dc.typeArticle
dc.identifier.doi10.1016/j.actatropica.2005.09.010
dc.description.abstractenAprospective study on 23 patients with American visceral leishmaniasis (VL), comparing clinical and laboratory parameters of 14 children (mean age of 3.85±3.39 years) to nine adults (27.4±10.90 years) was performed in S˜ao Lu´ıs, Maranh˜ao, Brazil, between August 2000 and July 2002. Data were collected at entrance (day 0), end of treatment, as well as 120 and 210 days after treatment using a protocol chart containing patient identification, clinical and laboratory data. N-Methylglucamine antimonate administered at the dose of 20 mg/Sb5+/kg/day for 20–30 days was successfully used in all patients. Patients were followed for 1 year after treatment, and no relapses were observed. A prolonged duration of the disease, lymphadenopathy and bleeding predominated in adult patients, while hepatomegaly and skin-mucosal pallor were more frequent in children. Disease was longer and more severe in adults than in children. Although both groups exhibited a trend toward normalization of hematological and biochemical parameters, more children returned sooner to normal values than adults. Difference in clinical or laboratory parameters between children and adults did not indicate the need for different clinical or therapeutic approaches.
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
dc.creator.affilliationUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, Brasil
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
dc.creator.affilliationUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, Brasil
dc.creator.affilliationUniversidade Federal do Maranhão. Departamento de Saúde Pública. São Luís, MA, Brasil
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
dc.creator.affilliationUniversidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil
dc.creator.affilliationFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
dc.creator.affilliationUniversidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil
dc.subject.enAmerican Visceral Leishmaniasis
dc.subject.enChildren
dc.subject.enAdults
dc.subject.enDelayed-type Hypersensitivity
dc.subject.enLymphoproliferative Response
dc.subject.decsLeishmaniose Visceral
dc.subject.decsCriança
dc.subject.decsAdulto
dc.subject.decsHipersensibilidade Tardia
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