Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/27853
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dc.contributor.authorCosta, Zelma B.
dc.contributor.authorMachado, Gustavo C.
dc.contributor.authorAvelino, Mariza M.
dc.contributor.authorGomes Filho, Clidenor
dc.contributor.authorMacedo Filho, Jose V.
dc.contributor.authorMinuzzi, Ana L.
dc.contributor.authorTurchi, Marilia D.
dc.contributor.authorStefani, Mariane M. A.
dc.contributor.authorSouza, Wayner Vieira de
dc.contributor.authorMartelli, Celina MT
dc.date.accessioned2018-08-06T12:33:07Z
dc.date.available2018-08-06T12:33:07Z
dc.date.issued2009
dc.identifier.citationCOSTA, Zelma B. et al. Prevalence and Risk Factors for Hepatitis C and HIV-1 Infections among Pregnant Women in Central Brazil. BMC Infectious Diseases, v. 9, p. 116, 27 jul. 2009.
dc.identifier.issn1471-2334
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/27853
dc.description.sponsorshipPrograma de Proteção a Gestante do Estado de Goiás, APAE e Projeto-OPAS / OMS BR / LOA / 0600188.001. A CMTM e a WVS receberam bolsas de estudo do CNPq (307963 / 2004-7) e (307484 / 2007-6), respectivamente.
dc.language.isoeng
dc.rightsopen access
dc.subject.otherVírus da imunodeficiência humana
dc.subject.otherMulher grávida
dc.subject.otherInfecção pelo Vírus da Imunodeficiência Humana
dc.subject.otherMulher negra
dc.subject.otherResultado Indeterminado
dc.titlePrevalence and risk factors for Hepatitis C and HIV-1 infections among pregnant women in Central Brazil
dc.typeArticle
dc.identifier.doi10.1186/1471-2334-9-116
dc.description.abstractenBACKGROUND: Hepatitis C (HCV) and human immunodeficiency virus (HIV) infections are a major burden to public health worldwide. Routine antenatal HIV-1 screening to prevent maternal-infant transmission is universally recommended. Our objectives were to evaluate the prevalence of and potential risk factors for HCV and HIV infection among pregnant women who attended prenatal care under the coverage of public health in Central Brazil. METHODS: Screening and counselling for HIV and HCV infections was offered free of charge to all pregnant women attending antenatal clinic (ANC) in the public health system, in Goiania city (~1.1 million inhabitants) during 2004-2005. Initial screening was performed on a dried blood spot collected onto standard filter paper; positive or indeterminate results were confirmed by a second blood sample. HCV infection was defined as a positive or indeterminate sample (EIA test) and confirmed HCV-RNA technique. HIV infection was defined according to standard criteria. Factors associated with HIV and HCV infections were identified with logistic regression. The number needed to screen (NNS) to prevent one case of infant HIV infection was calculated using the Monte Carlo simulation method. RESULTS: A total of 28,561 pregnant women were screened for HCV and HIV-1 in ANC. Mean maternal age was 23.9 years (SD = 5.6), with 45% of the women experiencing their first pregnancy. Prevalence of HCV infection was 0.15% (95% CI 0.11%-0.20%), and the risk increased with age (p < 0.01). The prevalence of anti-HIV infection was 0.09% (95% CI 0.06%-0.14%). Black women had a 4.9-fold (95% CI 1.42-16.95) greater risk of HIV-1 infection compared to non-black women. NNS to prevent one case of infant HIV infection ranged from 4,141 to 13,928. CONCLUSION: The prevalence of HIV and HCV infections were low among pregnant women, with high acceptability rates in the opt-in strategy in primary care. Older maternal age was a risk factor for HCV and antenatal HCV testing does not fulfill the requirements for screening recommendation. The finding of higher risk of HIV-1 infection among black women despite being in consonance with the HIV-1 ethnic pattern in some American regions cannot be ruled out to be a surrogate marker of socio-economic condition.
dc.creator.affilliationFederal University of Goiás. Faculty of Medicine. Goiás, Brazil.
dc.creator.affilliationFederal University of Goiás. Faculty of Medicine. Goiás, Brazil.
dc.creator.affilliationFederal University of Goiás. Faculty of Medicine. Goiás, Brazil.
dc.creator.affilliationSecretaria de Saúde do Estado de Goiás. Associação de Pais e Amigos dos Excepcionais de Goiânia – APAE. Goiânia, GO, Brazil.
dc.creator.affilliationSecretaria de Saúde do Estado de Goiás. Associação de Pais e Amigos dos Excepcionais de Goiânia – APAE. Goiânia, GO, Brazil.
dc.creator.affilliationSecretaria de Saúde do Estado de Goiás. Associação de Pais e Amigos dos Excepcionais de Goiânia – APAE. Goiânia, GO, Brazil.
dc.creator.affilliationFederal University of Goiás. Institute of Tropical Medicine and Public Health. Goiás, Brazil.
dc.creator.affilliationFederal University of Goiás. Institute of Tropical Medicine and Public Health. Goiás, Brazil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
dc.creator.affilliationFederal University of Goiás. Institute of Tropical Medicine and Public Health. Goiás, Brazil.
dc.subject.enHuman Immunodeficiency Virus
dc.subject.enPregnant Woman
dc.subject.enHuman Immunodeficiency Virus Infection
dc.subject.enBlack Woman
dc.subject.enIndeterminate Result
dc.subject.decsAdolescente
dc.subject.decsAdulto
dc.subject.decsIdade
dc.subject.decsFatores Brasil / epidemiologia
dc.subject.decsEstudos Transversais
dc.subject.decsFêmea
dc.subject.decsInfecções por HIV / epidemiologia
dc.subject.decsHIV-1
dc.subject.decsHepacivirus
dc.subject.decsHepatite C / epidemiologia
dc.subject.decsHumanos
dc.subject.decsTriagem em massa
dc.subject.decsVigilância da População
dc.subject.decsGravidez
dc.subject.decsComplicações na Gravidez Infecciosa / epidemiologia
dc.subject.decsComplicações na Gravidez Infecciosa / virologia
dc.subject.decsCuidados pré-natais
dc.subject.decsPrevalência
dc.subject.decsFatores de Risco
dc.subject.decsSaúde da mulher
dc.subject.decsAdulto jovem
Appears in Collections:PE - IAM - Artigos de Periódicos



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