Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/28335
Title: Trypanosoma cruzi (Kinetoplastida, Trypanosomatidae) genotypes in neotropical bats in Brazil
Authors: Lisboa, Cristiane Varella
Pinho, Ana Paula
Herrera, Heitor Miraglia
Gerhardt, Marconny
Cupolillo, Elisa
Jansen, Ana Maria
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil / EMBRAPA Pantanal. Corumbá, MS, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Leishmanioses. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil.
Abstract: Few studies have been conducted to investigate the role played by the order Chiroptera in the sylvatic transmission cycle of Trypanosoma cruzi or their putative association with the main genotypes of the parasite. Here, the purpose was to enlarge the knowledge of this issue, in this sense, 93 specimens of bats included in 4 families, respectively Molossidae, Noctilionidae, Phyllostomidae and Vespertilionidae collected in distinct regions of Brazil were submitted to fresh blood smears and hemocultures. No patent parasitemia was observed but positive hemocultures by T. cruzi were observed in 14% (13/93) of examined samples. The majority of the parasite isolates were obtained from Phyllostomus hastatus (80%) captured in one same buriti hollow palm tree in the Cerrado region. Multilocus enzyme electrophoresis (MLEE) analyses showed that the genetic distance among these isolates was 0.35, almost the same observed when all the isolates (excluding the reference strains) were analyzed (0.40). No correlation of zymodeme with bat genera, species or geographic region of its origin could be observed, moreover, correlation of zymodeme and genotype of the parasite was not strict. Ten out of 14 T. cruzi isolates obtained from bats corresponded to the TCII genotype. Chiropterans with TCI, TCII/TCIII mixed infection as well as Trypanosoma rangeli in single or mixed infections were observed. These results show that bats may harbor and are probably important maintainers of the main genotypes (TCI, TCII, TCIII/Z3) of T. cruzi. These results support the absence of an association of TCII with any mammal order and show that bats, mainly P. hastatus, may act as amplifier hosts of TCII subpopulations of T. cruzi.
Keywords: Trypanosoma cruzi
TCIII/Z3 genotype
Neotropical bats
TCI
TCII
keywords: Trypanosoma cruzi
morcegos neotropicais
Issue Date: 2008
Publisher: Elsevier
Citation: LISBOA, Cristiane Varella; et al. Trypanosoma cruzi (kinetoplastida, Trypanosomatidae) genotypes in neotropical bats in Brazil. Veterinary Parasitology, v.156, n.3-4, p.314-318, 2008.
DOI: 10.1016/j.vetpar.2008.06.004
ISSN: 0304-4017
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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