Tuberculosis elimination: where are we now?

University Dept of Infectious and Tropical Diseases. WHO Collaborating Centre for TB/HIV coinfection and for TB elimination. University of Brescia and Brescia Spedali Civili General Hospital. Brescia, Italy.
Centro de Investigación, Prevención y Tratamiento de Infecciones Respiratorias. Hospital Universitario de Monterrey. Monterrey, México.
Royal London Hospital. Barts Health NHS Trust. Division of Infection. London, UK.
Ministry of Health. Muscat, Oman.
Ministry of Health. Clinical Laboratories. Nicosia, Chipre.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inovações em Terapias, Ensino e Bioprodutos. Rio de Janeiro, RJ, Brasil.
World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases. Maugeri Care and Research Institute. IRCCS. Tradate, Italy.
World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases. Maugeri Care and Research Institute. IRCCS. Tradate, Italy / Public Health Consulting Group. Lugano, Switzerland.
Pneumology Dept. Maugeri Care and Research Institute. Tradate, Italy.
Pneumology Dept. Maugeri Care and Research Institute. Tradate, Italy / University of Insubria. Dept of Clinical and Experimental Medicine. Varese, Italy.
World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases. Maugeri Care and Research Institute. IRCCS. Tradate, Italy.

Resumo em Inglês

Tuberculosis (TB) still represents a major public health issue in spite of the significant impact of the efforts made by the World Health Organization (WHO) and partners to improve its control. In 2014 WHO launched a new global strategy (End TB) with a vision of a world free of TB, and a 2035 goal of TB elimination (defined as less than one incident case per million). The aim of this article is to summarise the theoretical bases of the End TB Strategy and to analyse progresses and persistent obstacles on the way to TB elimination.The evolution of the WHO recommended strategies of TB control (Directly Observed Therapy, Short Course (DOTS), Stop TB and End TB) are described and the concept of TB elimination is discussed. Furthermore, the eight core activities recently proposed by WHO as the milestones to achieve TB elimination are discussed in detail. Finally, the recently published experiences of Cyprus and Oman on their way towards TB elimination are described, together with the regional experience of Latin America.New prevention, diagnostic and treatment tools are also necessary to increase the speed of the present TB incidence decline.

Palavras-chave

Tuberculose
Saúde Pública

Palavras-chave em inglês

Tuberculosis
Public health

Editor

European Respiratory Society

Referência

MATTEELLI, Alberto; et al. Tuberculosis elimination: where are we now?. Eur Respir Rev, v. 27: 180035, 15p, 2018.

DOI

10.1183/16000617.0035-2018

ISSN

0905-9180

Use este identificador para citar ou linkar para este item: https://www.arca.fiocruz.br/handle/icict/28922

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