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CD4 RESPONSE UP TO 5 YEARS AFTER COMBINATION ANTIRETROVIRAL THERAPY IN HUMAN IMMUNODEFICIENCY VIRUS-INFECTED PATIENTS IN LATIN AMERICA AND THE CARIBBEAN
Luz, Paula M. et al. | Date Issued: 2015
Author
Luz, Paula M.
Belaunzarán-Zamudio, Pablo F.
Crabtree-Ramírez, Brenda
Caro-Vega, Yanink
Hoces, Daniel
Rebeiro, Peter F.
Blevins, Meridith
Pape, Jean W
Cortes, Claudia P.
Padgett, Denis
Cahn, Pedro
Veloso, Valdiléa G.
McGowan, Catherine C.
Grinsztejn, Beatriz
Shepherd, Bryan E.
Affilliation
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Department of Infectious Diseases. Ciudad de México, México.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Department of Infectious Diseases. Ciudad de México, México.
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Department of Infectious Diseases. Ciudad de México, México.
Vanderbilt University School of Medicine. Nashville, TN, USA.
Vanderbilt University School of Medicine. Nashville, TN, USA.
Weill Cornell Medical College. Department of Medicine. Division of Infectious Diseases. New York, USA.
University of Chile. School of Medicine. Santiago, Chile.
Universidad Nacional Autónoma de Honduras. Tegucigalpa, Honduras.
Fundación Huesped. Buenos Aires, Argentina.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Vanderbilt University School of Medicine. Nashville, TN, USA.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Vanderbilt University School of Medicine. Nashville, TN, USA.
Abstract
We describe CD4 counts at 6-month intervals for 5 years after combination antiretroviral therapy initiation among 12 879 antiretroviral-naive human immunodeficiency virus-infected adults from Latin America and the Caribbean. Median CD4 counts increased from 154 cells/mm(3) at baseline (interquartile range [IQR], 60-251) to 413 cells/mm(3) (IQR, 234-598) by year 5.
Keywords
cART
Cohort
Combination antiretroviral therapy
HIV/AIDS
Immune recovery
Inverse probability of censoring weights
Latin America
Caribbean
 
Citation
LUZ, Paula M. et al. CD4 Response Up to 5 Years After Combination Antiretroviral Therapy in Human Immunodeficiency Virus-Infected Patients in Latin America and the Caribbean. Open Forum Infectious Diseases, v. 2, n. 2, p. ofv079, 2015
DOI
10.1093/ofid/ofv079
ISSN
2328-8957