Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/30665
Title: The effects of vasoactive drugs on intestinal functional capillary density in endotoxemic rats: intravital video-microscopy analysis
Authors: Nacul, Flavio E.
Guia, Iris L.
Lessa, Marcos A.
Tibiriçá, Eduardo
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ. Brasil / Universidade Federal do Rio de Janeiro. Hospital Universitário. Medicina de Cuidados Intensivos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Investigação Cardiovascular. Rio de Janeiro, RJ. Brasil.
Abstract: The use of vasoactive drugs to restore arterial blood pressure in patients with septic shock remains a cornerstone of intensive care medicine. However, vasopressors can accentuate the hypoperfusion of the gut during septic shock, allowing bacterial translocation and endotoxemia. In this study, we compared the effects of different vasoactive drugs on intestinal microcirculation and tissue oxygenation, independent of the effects of fluid therapy, in a rat model of endotoxemic shock.
Keywords: Endotoxemic Rats
Vasoactive Drugs
Intestinal Functional Capillary Density
Video-Microscopy Analysis
keywords: Ratos endotoxêmicos
Drogas Vasoativas
Densidade Capilar Funcional Intestinal
Análise de videomicroscopia
Issue Date: 2010
Publisher: International Anesthesia Research Society
Citation: NACUL, Falvio E. et al. The Effects of Vasoactive Drugs on Intestinal Functional Capillary Density in Endotoxemic Rats: Intravital Video-Microscopy Analysis. Anesthesia & Analgesia, v.110, n. p.547-554, Feb. 2010.
DOI: 10.1213/ANE.0b013e3181c88af1
ISSN: 0003-2999
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

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