Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/31040
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dc.contributor.authorCosta, Emmanoel Vilaça
dc.contributor.authorPinheiro, Maria Lúcia Belém
dc.contributor.authorSilva, Jefferson Rocha de Andrade
dc.contributor.authorMaia, Beatriz Helena Lameiro de Noronha Sales
dc.contributor.authorDuarte, Marta Cristina Teixeira
dc.contributor.authorAmaral, Ana Cláudia Fernandes
dc.contributor.authorMachado, Gérzia Maria de Carvalho
dc.contributor.authorLeon, Leonor Laura
dc.date.accessioned2019-01-15T14:05:53Z
dc.date.available2019-01-15T14:05:53Z
dc.date.issued2009
dc.identifier.citationCOSTA, Emmanoel Vilaça et al. Antimicrobial and Antileishmanial acvtivity of essential oil from the leaves of Annona foetida. Qumi. Nova, v. 32, n. 1, p. 78-81, 2009.
dc.identifier.issn0100-4042
dc.identifier.urihttps://www.arca.fiocruz.br/handle/icict/31040
dc.language.isoeng
dc.publisherSociedade Brasileira de Química
dc.rightsopen access
dc.subject.otherAnnona foetida
dc.subject.otherComposição de óleo essencial
dc.subject.otherAtividades antimicrobiana e antileishmanial
dc.titleAntimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (ANNONACEAE)
dc.typeArticle
dc.description.abstractenThe essential oil from leaves of Annona foetida obtained by hydrodistillation was analyzed by GC/FID and GC/MS. The results showed that the major constituents were bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and α-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages.
dc.creator.affilliationUniversidade Federal do Amazonas. Departamento de Química. Manaus, AM, Brasil.
dc.creator.affilliationUniversidade Federal do Amazonas. Departamento de Química. Manaus, AM, Brasil.
dc.creator.affilliationUniversidade Federal do Amazonas. Departamento de Química. Manaus, AM, Brasil.
dc.creator.affilliationUniversidade Federal do Paraná. Departamento de Química. Curitiba, PR, Brasil.
dc.creator.affilliationUniversidade Estadual de Campinas. Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas. Campinas, SP, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Farmanguinhos. Departamento de Produtos Naturais. Rio de Janeiro, RJ, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.
dc.creator.affilliationFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.
dc.subject.enAnnona foetida
dc.subject.enAntimicrobial and antileishmanial activities
dc.subject.enEssential oil composition
dc.identifier.eissn1678-7064
Appears in Collections:Farmanguinhos - Artigos de Periódicos
IOC - Artigos de Periódicos

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