Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/31121
Title: Description of a Widespread Outbreak of Aseptic Meningitis Due to Echovirus 30 in Rio de Janeiro State, Brazil
Authors: Pinto Junior, Vitor Laerte
Rebelo, Maria Cristina
Costa, Eliane Veiga de
Silva, Edson Elias da
Bóia, Márcio Neves
Affilliation: Fundação Oswaldo Cruz. Diretoria Regional de Brasília. Brasília, DF, Brasil.
Instituto Estadual de Infectologia São Sebastião. Laboratório de Referência Estadual para Meningites. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovirus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Enterovirus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Pós-Graduação em Medicina Tropical. Rio de Janeiro, RJ, Brasil.
Abstract: Echovirus 30 belongs to the genus Enterovirus and is widely associated with aseptic meningitis (AM) outbreaks. In Brazil epidemics due to this serotype were reported in several states but in Rio de Janeiro, before this study, it was only involved in sporadic episodes. We retrospectively collected data from AM notifications charts and enterovirus isolation database from Rio de Janeiro State Health Department (RJSHD) and Enterovirus Reference Laboratory in the year of 2005. An outbreak of AM was detected during March, April and May associated with a high cell culture isolation rate for echovirus 30 (17.4%). Male children with ages varying from 1 to 9 years were more affected. Of the 22 patients with confirmed echovirus 30 disease, clinical information was available in eight; fever, headache and vomiting were the most common manifestations. CSF analysis showed a typical pattern of viral infection with median of cellularity of 100 cells/mm³ and mononuclear cell predominance in 64.7% of the cases. The median of protein and glucose levels of 49 mg/dL and 56.5 mg/dL. The fatality rate was null. Despite its benign course and the lack of treatment options, aseptic meningitis surveillance is crucial for early identification of causative agents of outbreaks, which helps to avoid additional testing and inappropriate use of antimicrobials. Key-Words: Aseptic meningitis, enterovirus, echoviruses, cerebrospinal fluid.
Keywords: Description
Widespread outbreak
Aseptic meningitis
Echovirus 30
Rio de Janeiro
keywords: Meningite asséptica
Surto disseminado
Surto
Ecovírus 30
Rio de Janeiro
Descrição
Issue Date: 2009
Publisher: Elsevier
Citation: PINTO JUNIOR, Vitor Laerte; et al. Description of a Widespread Outbreak of Aseptic Meningitis Due to Echovirus 30 in Rio de Janeiro State, Brazil. Brazilian Journal of Infectious Diseases, v. 13, n. 5, p. 367-370, 2009.
ISSN: 1413-8670
Copyright: restricted access
Appears in Collections:BSB - Artigos de Periódicos
IOC - Artigos de Periódicos

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